Protein Alignment Ret and R09D1.13

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_496022.1
• Gene: R09D1.13 / 187740
• WormBaseID: WBGene00011169
• Length: 388
• Species: Caenorhabditis elegans
• Alignment Length: 394
• Identity: 109/394 - (27%)
• Similarity: 187/394 - (47%)
• Gaps: 49/394 - (12%)

  Fly   695 CMFFVITCPLLFVLLLLCLLIAQRKMLQR---RLGKQSMTTSSKQALPESGGGDFALMPLQSGFR 756
            |:|..:   :||....:...:.::|...|   |.||:...|...:..| ....|..:..     .
 Worm    10 CIFIAV---ILFAFACILQKVYKKKTQDRPALRRGKRGSITEQIELTP-INKDDMCIRD-----N 65

  Fly   757 FESGDAKWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVK---------MLKKGSN 812
            ...|:...|.....|:..:||..|.|.::.:|..       .|...|.:         ::|:..|
 Worm    66 ISIGNIPVEIDPSNLKFSSVLENGYFCKIRRGTL-------NINVTAEEKNSNKLVDVLVKRPKN 123

  Fly   813 SVEYMALLSEFQLLQEVS-HPNVIKLLGACTSSEAPLLII-EYARYGSLRSYLRLSR-KIECAGV 874
            .:|...|.:|..:|:.:. ||||:.|:|..:......::: |....|:|:..|:::: ..|..||
 Worm   124 HIEKEMLENELTILRLIGRHPNVLALIGYTSPMFGRTVVVYESVELGNLQHVLKITKNNFELVGV 188

  Fly   875 ---DFADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDV 936
               :|: |::...|..:.:||:||..||.||:.:.::||.||.||:.|...|..:|::|||:::|
 Worm   189 PETEFS-GLDEFCVSDLHSFAFQIANGMEYLTHIPVIHRFLALRNIFLKRNKTIRIANFGLSKNV 252

  Fly   937 YEDDAYLKRSRDR-VPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAP--QNLW 998
              :|..:..|.|. ||:.||||||..:.::..|:|||||||..:||.:||..||..:..  .:|.
 Worm   253 --NDYRIIDSMDTPVPLYWMAPESYNELIFNEKTDVWSFGVCLYELYSLGEDPYENVKTLFDHLM 315

  Fly   999 SLLKTGYRMDRPENC-SEAVYSIVRTCWADEPNGRPSFKFLASEFEK--------LLGNNAKYID 1054
            ..|:.|.|:.:|:.. |..::..::.||..:|..||.|...|..|:.        ||......:.
 Worm   316 EYLEKGNRLSKPKYIDSPEIFDFMKICWNFKPETRPCFSDCAQFFKSHLQEFPPALLEQTQSELK 380

  Fly  1055 LETN 1058
            ||:|
 Worm   381 LESN 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	92/305 (30%)
R09D1.13	NP_496022.1	STYKc	80..360	CDD:214568	89/289 (31%)