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Protein Alignment Ret and spe-8

DIOPT Version :10

Sequence 1:	NP_477044.1	Gene:	Ret / 43875	FlyBaseID:	FBgn0011829	Length:	1235	Species:	Drosophila melanogaster
Sequence 2:	NP_490680.1	Gene:	spe-8 / 171606	WormBaseID:	WBGene00004962	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	323	Identity:	103/323 - (31%)
Similarity:	165/323 - (51%)	Gaps:	31/323 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   750 PLQSGFRFESGDAK--WEFPREKLQLDTVLGEGEFGQVLKG-FATEIAGLPGITTVAVKMLKKGS 811
            |:..|.....|.|:  |:...|::.|:..||||:||:|.|| ..|.:...|  .|||||.|.:..
Worm   194 PIYEGMTLICGLARHGWQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAP--VTVAVKTLHQNH 256

  Fly   812 NSV-EYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVD 875
            .|. |.:..|.|..::..:|||||||..|.||..|..::::|:....||...| ||::
Worm   257 LSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDAL-LSKE------- 313

  Fly   876 FADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDD 940
                 |.|:.:..:.:.:....|:.||...:::|||:||||.||...||.|||||||:   .:..
Worm   314 -----EKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLS---VKGV 370

  Fly   941 AYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYP--GIAPQNLWSLLKT 1003
            |..:|....:|||:||||:|...:|::.||::|:|.|.:|:.|.|.:|:.  |:....|...: .
Worm   371 AIKERKGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTPFETCGLRGNELRKAI-I 434

  Fly  1004 GYRMDRPENCSEAVY--SIVRTCWADEPNGRPSFKFLASEFEKLLGNNAKYIDLETNAVSNPL 1064
            |.|:.........|:  :|.......|...|.|.|.:...|::.:|    :.::||:.:.:.|
Worm   435 GKRISLAVEVELPVFIANIFEQSRQYETEDRISSKQIIQIFKEEVG----FHEIETSGILHKL 493

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.