Protein Alignment Ret and Lyn

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_001104566.1
• Gene: Lyn / 17096
• MGIID: 96892
• Length: 512
• Species: Mus musculus
• Alignment Length: 277
• Identity: 109/277 - (39%)
• Similarity: 159/277 - (57%)
• Gaps: 21/277 - (7%)

  Fly   764 WEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQE 828
            ||.|||.::|...||.|:||:|..|:..      ..|.||||.||.|:.||:  |.|.|..|::.
Mouse   240 WEIPRESIKLVKKLGAGQFGEVWMGYYN------NSTKVAVKTLKPGTMSVQ--AFLEEANLMKT 296

  Fly   829 VSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTFAW 893
            :.|..:::|....|..|...:|.|:...|||..:|:            :|....|.:..::.|:.
Mouse   297 LQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLK------------SDEGGKVLLPKLIDFSA 349

  Fly   894 QICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPE 958
            ||.:||||:.....:||||.|.|||:::..:|||:||||.| |.||:.|..|...:.|:||.|||
Mouse   350 QIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLAR-VIEDNEYTAREGAKFPIKWTAPE 413

  Fly   959 SLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRT 1023
            ::....:|.||||||||:|.:|::|.|..||||....::.|.|..||||.|.|||.:.:|.|::.
Mouse   414 AINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKM 478

  Fly  1024 CWADEPNGRPSFKFLAS 1040
            ||.::...||:|.:|.|
Mouse   479 CWKEKAEERPTFDYLQS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	104/271 (38%)
Lyn	NP_001104566.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45
		SH3_Lyn	67..122	CDD:212937
		SH2_Src_Lyn	125..225	CDD:198227
		PTKc_Lyn	239..510	CDD:270657	109/277 (39%)