Protein Alignment Ret and LOC1280989

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_061514024.1
• Gene: LOC1280989 / 1280989
• VectorBaseID: AGAMI1_006242
• Length: 731
• Species: Anopheles gambiae
• Alignment Length: 464
• Identity: 151/464 - (32%)
• Similarity: 243/464 - (52%)
• Gaps: 75/464 - (16%)

  Fly   655 NETEAEPLLGVRRGTP--PNQPLQDPMLLGVLNVAGFECDRS-----CMFFVITCPLLFV---LL 709
            |.|...|.:.....||  |..|||..:..|.:.:.....:.:     .:..:|:..::||   |:
Mosquito   263 NTTAPHPTIAGESSTPTTPKLPLQPTITTGTVPIHAHPHEETNTVKILLPVIISVAIIFVTAGLI 327

  Fly   710 LLCLLIAQRKMLQRRLGKQSMTTSSKQALPESGGGDFALM---------------PLQSGFRF-- 757
            .:|........|.:.|.|::....:|::...:|..:....               |:....|:
Mosquito   328 AICFFRKYLCALSKTLKKKNKIDKAKKSNQSNGSSNITSTAEDSRNSIGLSHWTGPMAFSNRYTS 392

  Fly   758 ------------------ESGDA----KWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGIT 800
                              ||..:    :|||||.:|::..:||||.||||.:..||:|.|..|::
Mosquito   393 PWERDTNGHLQATSQLSEESNGSIVKDRWEFPRHRLKVFNILGEGAFGQVWRCEATDIDGHEGVS 457

  Fly   801 TVAVKMLKKGSNSVEYMALLSEFQLLQEVS-HPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLR 864
            ..|||.||:.::..|...||||.|:|:.:. |.||::|||.||..:...:|:||...|.|:::||
Mosquito   458 VTAVKTLKENASEAERNDLLSELQVLKSLEPHINVVRLLGCCTEKDPIFVILEYVNMGKLQTFLR 522

  Fly   865 LSR------------KIECAGVDFADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNV 917
            .||            ||..:|             .:.:|.:|:.:||.:|:.|.::||||||||:
Mosquito   523 NSRVEKHYGNTHGKSKILTSG-------------DLTSFMYQVARGMDFLTSLGIIHRDLAARNI 574

  Fly   918 LLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELI 982
            |:.|...||::|||..||:.....|.::|..|:|::|||.|||.|:::|.|||:||||:|.||::
Mosquito   575 LITDDHTCKVADFGFARDIVTSKVYERKSEGRLPIRWMATESLYDNIFTVKSDIWSFGILMWEIV 639

  Fly   983 TLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLG 1047
            |||::||||||..::...::.|||:::||:|...:|:|:..|||.:||.||.|..:....::||.
Mosquito   640 TLGSTPYPGIAAADVMRKVRDGYRLEKPEHCRRELYNIMFYCWAADPNERPGFPEVVEMLDRLLQ 704

  Fly  1048 NNAKYIDLE 1056
            ....||:||
Mosquito   705 TETDYIELE 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	118/291 (41%)
LOC1280989	XP_061514024.1	None