Protein Alignment Ret and Src64B

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_061508350.1
• Gene: Src64B / 1277104
• VectorBaseID: AGAMI1_012487
• Length: 538
• Species: Anopheles gambiae
• Alignment Length: 284
• Identity: 105/284 - (36%)
• Similarity: 156/284 - (54%)
• Gaps: 25/284 - (8%)

  Fly   763 KWEFPREKLQLDTVLGEGEFGQVLKG-FATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLL 826
            |||..|.::||...||.|.||:|..| :...|       .||||.|::|:.|.:  |.|.|..::
Mosquito   262 KWEINRNEIQLIRKLGHGNFGEVYYGKWRNNI-------EVAVKTLREGTMSTQ--AFLQEAAIM 317

  Fly   827 QEVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTF 891
            ::..|..::.|...|:..|...::.||...|||..:||.           .|| :.:..:.::..
Mosquito   318 KKFRHSRLVALYAVCSKEEPIYIVQEYMSKGSLLDFLRT-----------GDG-QFLQFEDLIYI 370

  Fly   892 AWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMA 956
            |.|:..||.||...:|:||||||||||:.:..:.||.||||.| |..||.|..:...|.||||.|
Mosquito   371 AAQVASGMEYLELKQLIHRDLAARNVLIGENNVAKICDFGLAR-VIADDEYCPKQGSRFPVKWTA 434

  Fly   957 PESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRP--ENCSEAVYS 1019
            ||::....::.||||||:|:|..||.|.|..||||:..:.:...::.||||.:|  .:..:.:||
Mosquito   435 PEAIVYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIEQIERGYRMPKPTAHHLPDDIYS 499

  Fly  1020 IVRTCWADEPNGRPSFKFLASEFE 1043
            ::..||...|:.||:|:||...|:
Mosquito   500 LMLKCWDAIPDKRPTFEFLNHYFQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	101/277 (36%)
Src64B	XP_061508350.1	None