Protein Alignment ras and IMD4

DIOPT Version :9

• Sequence 1: NP_001356940.1
• Gene: ras / 43873
• FlyBaseID: FBgn0003204
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_013656.1
• Gene: IMD4 / 854948
• SGDID: S000004520
• Length: 524
• Species: Saccharomyces cerevisiae
• Alignment Length: 530
• Identity: 312/530 - (58%)
• Similarity: 396/530 - (74%)
• Gaps: 19/530 - (3%)

  Fly    19 SAAPA--------IQTKSTTGFDAELQDGLSCKELFQNGE--GLTYNDFLILPGYIDFTAEEVDL 73
            ||||.        ::|.|:       :||||.:||..:..  ||||||||:|||.::|.:..|.|
Yeast     2 SAAPLDYKKALEHLKTYSS-------KDGLSVQELMDSTTRGGLTYNDFLVLPGLVNFPSSAVSL 59

  Fly    74 SSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMR 138
            .:.|||.:||..|.||||||||||::|||.|||.||||.|||||||:.||..|.|||.:::||:.
Yeast    60 QTKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHNCTPKEQASMVKKVKMFENGFIN 124

  Fly   139 DPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFRENQPEVLLADIMTTE 203
            .|.|:|||.|||:|...:||.||:|:||||:||..|||:|:||||||.|.|:. .::::::||..
Yeast   125 SPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPGKLVGLVTSRDIQFLEDD-SLVVSEVMTKN 188

  Fly   204 LVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKD-SNKQLLVGA 267
            .||...||.|...|.||:::|||||.||:..|.||:|::|.||.|.::||.|||. :.||||.||
Yeast   189 PVTGIKGITLKEGNEILKQTKKGKLLIVDDNGNLVSMLSRADLMKNQNYPLASKSATTKQLLCGA 253

  Fly   268 AIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNL 332
            ||||...||.||.|||..|:||:||||||||||:|:.|||:||||:|:|::|.|||.||.||.||
Yeast   254 AIGTIEADKERLRLLVEAGLDVVILDSSQGNSVFQLNMIKWIKETFPDLEIIAGNVATREQAANL 318

  Fly   333 IDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIA 397
            |.||.||||:|||||||||||||||||.||.||||.|..:|.|||||.:||||:|:||||.||:|
Yeast   319 IAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCQFANQFGVPCMADGGVQNIGHITKALA 383

  Fly   398 LGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKV 462
            ||:|.||||.:||||:|:|||||:.||.|||.||||||::||::...||.|.:..|.:|.|.:.|
Yeast   384 LGSSTVMMGGMLAGTTESPGEYFYKDGKRLKAYRGMGSIDAMQKTGNKGNASTSRYFSESDSVLV 448

  Fly   463 AQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVH 527
            ||||||::|||||:.:::|||..||||||||||..|:..|::.:.||::||..||.||||||.||
Yeast   449 AQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCESLTSLKENVQNGEVRFEFRTASAQLEGGVH 513

  Fly   528 GLFSYEKRLF 537
            .|.||||||:
Yeast   514 NLHSYEKRLY 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	301/497 (61%)
IMD4	NP_013656.1	PTZ00314	21..519	CDD:240355	301/498 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	589	1.000	Domainoid score	I27
eggNOG	1	0.900	-	-		E1_COG0516
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68096
Inparanoid	1	1.050	606	1.000	Inparanoid score	I129
Isobase	1	0.950	-	0	Normalized mean entropy	S236
OMA	1	1.010	-	-		QHG62889
OrthoFinder	1	1.000	-	-		FOG0001014
OrthoInspector	1	1.000	-	-		otm46774
orthoMCL	1	0.900	-	-		OOG6_100534
Panther	1	1.100	-	-	LDO	PTHR11911
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R605
SonicParanoid	1	1.000	-	-		X605
TreeFam	1	0.960	-	-
	15	14.810