DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ras and AT1G79470

DIOPT Version :9

Sequence 1:	NP_001356940.1	Gene:	ras / 43873	FlyBaseID:	FBgn0003204	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_178065.1	Gene:	AT1G79470 / 844285	AraportID:	AT1G79470	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	246/514 - (47%)
Similarity:	326/514 - (63%)	Gaps:	26/514 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LQDGLSCKELFQNGEGLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEM 100
            |:||....:||..|...||:|.:.||.:|||:.:.|.||:.|::.:.|..|.||||||||:||.|
plant     4 LEDGFPADKLFAQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSRRVPLSIPCVSSPMDTVSESHM 68

  Fly   101 AIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGF---- 161
            |.|||..|||||:|:||....||..:.:.|..||....|..|..|...:.. |:|...:.|
plant    69 AAAMASLGGIGIVHYNCGIAAQASIIRQAKSLKHPIASDAGVKFPEYEITS-LDAFGPSSFVFVE 132

  Fly   162 -TGYPVTENGKLGGKLLGMVT-SRDIDFRENQPEVLLADIM---TTELVTAPNGINLPTANAILE 221
             ||...|.      ||||.|| |:.......|.|:.:.|.|   .:.....|..|:......:||
plant   133 QTGTMTTP------KLLGYVTKSQWKRMNYEQREMKIYDYMKSCDSSDYCVPWEIDFEKLEFVLE 191

  Fly   222 KSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDS---NKQLLVGAAIGTRSEDKARLALLV 283
            ..:|| ..::.:.||.|.::.:.|:::.:.||.:...:   :.:.:||||||||..||.||..||
plant   192 DKQKG-FVVLERDGETVNVVTKDDIQRVKGYPKSGPGTVGPDGEWMVGAAIGTRESDKERLEHLV 255

  Fly   284 ANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGS 348
            ..||:.::||||||||:||:|||||:|:|||||.||||||||..||:|||.||||||||||||||
plant   256 NVGVNAVVLDSSQGNSIYQLEMIKYVKKTYPELDVIGGNVVTMYQAQNLIQAGVDGLRVGMGSGS 320

  Fly   349 ICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTS 413
            ||.||||.|.|..||||||:|.:.|.|.|:||||||||.:.||||||:.||||.|||||.|||::
plant   321 ICTTQEVCAVGRGQATAVYKVCSIAAQSGIPVIADGGISNSGHIVKALVLGASTVMMGSFLAGST 385

  Fly   414 EAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLR 478
            ||||.|.:::|.|:||||||||||||.:|.      .:.|..:..|:|:||||.|::.||||||:
plant   386 EAPGGYEYTNGKRIKKYRGMGSLEAMTKGS------DQRYLGDQTKLKIAQGVVGAVADKGSVLK 444

  Fly   479 YLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF 537
            .:||....::...||:||:|:.....::.:..||...||.:||:||.||||.||||:.|
plant   445 LIPYTMHAVKQGFQDLGASSLQSAHGLLRSNILRLEARTGAAQVEGGVHGLVSYEKKSF 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	241/506 (48%)
AT1G79470	NP_178065.1	PLN02274	1..503	CDD:215154	245/512 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	421	1.000	Domainoid score	I121
eggNOG	1	0.900	-	-		E1_COG0516
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68096
Inparanoid	1	1.050	447	1.000	Inparanoid score	I395
OMA	1	1.010	-	-		QHG62889
OrthoDB	1	1.010	-	-		D618077at2759
OrthoFinder	1	1.000	-	-		FOG0001014
OrthoInspector	1	1.000	-	-		otm3310
orthoMCL	1	0.900	-	-		OOG6_100534
Panther	1	1.100	-	-	O	PTHR11911
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X605
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840