DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ras and AT1G16350

DIOPT Version :9

Sequence 1:	NP_001356940.1	Gene:	ras / 43873	FlyBaseID:	FBgn0003204	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_173085.1	Gene:	AT1G16350 / 838204	AraportID:	AT1G16350	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	248/516 - (48%)
Similarity:	340/516 - (65%)	Gaps:	23/516 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 TGFDAELQDGLSCKELFQNGEGLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDT 94
            :||    :||.|.::||..|...||:|.:.||.:|||:.:.|.||:.|:|.:.|..|.|:|||||
plant     2 SGF----EDGFSAEKLFSQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSKRVPLSIPCVASPMDT 62

  Fly    95 VTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKN 159
            |:||.||.|||..|||||:|:||..:.||..:...|..:.....|.....|.:.:|.|.:.
plant    63 VSESHMAAAMAALGGIGIVHYNCDIDTQASVIRHAKSLQVPIASDAVFKCPEHQIGSVDDF---- 123

  Fly   160 GFTGYP-VTENGKLGGKLLGMVTSRD-IDFRENQPEVLLADIMTT---ELVTAPNGINLPTANAI 219
            |.:.:. |::.|.|..||||.|:..: ...:::|.||.:.|.|.:   :....|..|:|....|:
plant   124 GPSSFVFVSQTGTLTPKLLGYVSKSEWSSMKDDQKEVKIYDYMKSCENKDYYVPWDIDLDKIEAV 188

  Fly   220 LEKSKKGKLPIVNQAGELVAMIARTDLKKARSYP---NASKDSNKQLLVGAAIGTRSEDKARLAL 281
            ||..:|| ..::.:.||.|.::.:.|:::.:.||   :.:..::|:.:||||||||..||.||..
plant   189 LEDKQKG-FVVLEKEGETVNVVTKDDVERVKGYPKLGSGTVGADKKWMVGAAIGTRESDKERLEH 252

  Fly   282 LVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGS 346
            ||..|.:|::||||||||:||:|||||:|.|||||.|:||||||..||:|||.||||||||||||
plant   253 LVKAGANVVVLDSSQGNSIYQLEMIKYVKNTYPELDVVGGNVVTMYQAENLIKAGVDGLRVGMGS 317

  Fly   347 GSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAG 411
            ||||.||||.|.|..||||||:|||.|.|.||||||||||.:.||||||:.||||.|||||.|||
plant   318 GSICTTQEVCAVGRGQATAVYKVSTLAAQHGVPVIADGGISNSGHIVKALVLGASTVMMGSFLAG 382

  Fly   412 TSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSV 476
            ::||||.|.:.:|.|:||||||||||||.:|.      .:.|..:..|:|:||||.|::.|||||
plant   383 STEAPGAYEYRNGRRVKKYRGMGSLEAMTKGS------DQRYLGDTAKLKIAQGVVGAVADKGSV 441

  Fly   477 LRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF 537
            |:::||....::...||:||:|:....:::.:..||...||.:||:||.:|||.||||:.|
plant   442 LKFIPYTMHAVKQGFQDLGASSLQSAHELLRDNTLRLEARTGAAQIEGGIHGLVSYEKKSF 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	242/502 (48%)
AT1G16350	NP_173085.1	PLN02274	1..502	CDD:215154	247/514 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	421	1.000	Domainoid score	I121
eggNOG	1	0.900	-	-		E1_COG0516
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68096
Inparanoid	1	1.050	447	1.000	Inparanoid score	I395
OMA	1	1.010	-	-		QHG62889
OrthoDB	1	1.010	-	-		D618077at2759
OrthoFinder	1	1.000	-	-		FOG0001014
OrthoInspector	1	1.000	-	-		otm3310
orthoMCL	1	0.900	-	-		OOG6_100534
Panther	1	1.100	-	-	LDO	PTHR11911
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X605
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840