Protein Alignment ras and PRKAG1

DIOPT Version :9

• Sequence 1: NP_001356940.1
• Gene: ras / 43873
• FlyBaseID: FBgn0003204
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_005269076.1
• Gene: PRKAG1 / 5571
• HGNCID: 9385
• Length: 368
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 57/278 - (20%)
• Similarity: 107/278 - (38%)
• Gaps: 77/278 - (27%)

  Fly    85 APLVSSP------MDTVTESEMAIAMALCGGIGIIHH---NCTPEYQALEVHKVKKYKHGFMRD- 139
            |||..|.      |.|:|:.           |.|:|.   :...:...||.||::.::..:::|
Human   109 APLWDSKKQSFVGMLTITDF-----------INILHRYYKSALVQIYELEEHKIETWREVYLQDS 162

  Fly   140 --PSV-MSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFRE------NQPEVL 195
              |.| :||..::.|.:.:..:|.....||.: .:.|..|..:...|.:.|.:      .:||.:
Human   163 FKPLVCISPNASLFDAVSSLIRNKIHRLPVID-PESGNTLYILTHKRILKFLKLFITEFPKPEFM 226

  Fly   196 LADIMTTELVTAPNGINLPT------ANAILEKSKKGKLPIVNQAGELVAMIARTD---LKKARS 251
            ...:...::.|..|...:.|      |..|..:.:...||:|::.|.:|.:.::.|   |...::
Human   227 SKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKT 291

  Fly   252 YPNASKDSNKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIK-YIKETYPE 315
            |                                |.:||.:..:.|..|.|...::| |:.||
Human   292 Y--------------------------------NNLDVSVTKALQHRSHYFEGVLKCYLHET--- 321

  Fly   316 LQVIGGNVVTRAQAKNLI 333
            |:.|...:| .|:...|:
Human   322 LETIINRLV-EAEVHRLV 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	57/278 (21%)
PRKAG1	XP_005269076.1	CBS_pair_5	92..212	CDD:239990	26/114 (23%)
		CBS	93..210	CDD:223591	26/112 (23%)
		CBS	164..284	CDD:223591	25/120 (21%)
		CBS_pair_28	239..358	CDD:240012	27/136 (20%)
		CBS	240..356	CDD:223591	27/135 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910