Protein Alignment ras and impdh1

DIOPT Version :9

• Sequence 1: NP_001356940.1
• Gene: ras / 43873
• FlyBaseID: FBgn0003204
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_031753820.1
• Gene: impdh1 / 550037
• XenbaseID: XB-GENE-957448
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 359/545 - (65%)
• Similarity: 430/545 - (78%)
• Gaps: 21/545 - (3%)

  Fly    10 NGFVESTSSSAAPAIQTKSTTGFDAEL--------------QDGLSCKELFQNGEGLTYNDFLIL 60
            :|.:....::|.....|:...|::.|.              :|||:.:.||.|.:||||||||||
 Frog    49 SGHLHGHETAAQRYSATRLQAGYEPESMADYLISGGTGYVPEDGLTAQHLFANSDGLTYNDFLIL 113

  Fly    61 PGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALE 125
            ||:|||||:||||:|.||:.:||:.||:||||||||||:|||||||.|||||||||||||:||.|
 Frog   114 PGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTESDMAIAMALMGGIGIIHHNCTPEFQANE 178

  Fly   126 VHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDF-RE 189
            |.||||::.||:.||.|||..:|||||.||:.::||:|.||||.||:|.||:|:|||||||| .|
 Frog   179 VRKVKKFEQGFITDPVVMSLNHTVGDVFEAKNRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTE 243

  Fly   190 NQPEVLLADIMT--TELVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSY 252
            ......|:::||  .|||.||.|:.|..||.||::||||||||||.:.||||:||||||||.|.|
 Frog   244 KDYSTYLSEVMTKRDELVVAPAGVTLKEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDY 308

  Fly   253 PNASKDSNKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQ 317
            |.||||..||||.|||||||.:||.||.||...||||::|||||||||||:.||.|||:.|||||
 Frog   309 PLASKDCRKQLLCGAAIGTREDDKYRLDLLTQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQ 373

  Fly   318 VIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIA 382
            |:||||||.||||||||||||.||||||.|||||||||||||.||.||||:|:.|||:|||||||
 Frog   374 VVGGNVVTAAQAKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIA 438

  Fly   383 DGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGA 447
            |||||::||:|||:|||||.||||||||.|:|||||||||||||||||||||||:|||    |..
 Frog   439 DGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAME----KNT 499

  Fly   448 AMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLR 512
            :..:.|.:|.||:||||||||||.||||:.:::|||..|:||.||||||.|::.||.|:|:|:|:
 Frog   500 SSQKRYFSEGDKVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELK 564

  Fly   513 FMKRTHSAQLEGNVHGLFSYEKRLF 537
            ..|||.|||:||.||||.||||||:
 Frog   565 LEKRTMSAQVEGGVHGLHSYEKRLY 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	349/497 (70%)
impdh1	XP_031753820.1	PTZ00314	89..585	CDD:240355	349/499 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	668	1.000	Domainoid score	I146
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68096
Inparanoid	1	1.050	699	1.000	Inparanoid score	I658
OMA	1	1.010	-	-		QHG62889
OrthoDB	1	1.010	-	-		D281746at33208
OrthoFinder	1	1.000	-	-		FOG0001014
OrthoInspector	1	1.000	-	-		otm48426
Panther	1	1.100	-	-	O	PTHR11911
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R605
SonicParanoid	1	1.000	-	-		X605
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110