Protein Alignment ras and GMPR2

DIOPT Version :9

• Sequence 1: NP_001356940.1
• Gene: ras / 43873
• FlyBaseID: FBgn0003204
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001269951.1
• Gene: GMPR2 / 51292
• HGNCID: 4377
• Length: 427
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 87/320 - (27%)
• Similarity: 144/320 - (45%)
• Gaps: 65/320 - (20%)

  Fly   265 VGAAIGTRSEDKARL--ALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRA 327
            :.|:.||.|.|..:|  .|.....|..|.||.:.|.|.:.||.:|.:::.:|:..::.|||||..
Human   117 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGE 181

  Fly   328 QAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHI 392
            ..:.||.:|.|.::||:|.||:|.|::....|.||.:||.:.:..|......:|:|||....|.:
Human   182 MVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDV 246

  Fly   393 VKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRY----- 452
            .||...||..||:|.:|||.||:.||....||.:.|.:.||.|..||:: .|.|.|..||
Human   247 AKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK-YAGGVAEYRYVWRPR 310

  Fly   453 -----------------YHNE------------MDK-----------------MKVAQGVSGSIV 471
                             |.::            ::|                 ::.::|.:..:.
Human   311 SLVIVWRQNSWLLRGGWYSSQRSMVNRGSMLGSVEKSLGLRNPEGEDNKVFPTLRASEGKTVEVP 375

  Fly   472 DKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFS 531
            .||.|...:..:..|::.:|..:||..:.:|           .:||...::...|:.:||
Human   376 FKGDVEHTIRDILGGIRSTCTYVGAAKLKEL-----------SRRTTFIRVTQQVNPIFS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	87/320 (27%)
GMPR2	NP_001269951.1	PRK05096	21..424	CDD:235343	85/318 (27%)
		IMPDH	28..415	CDD:238223	84/309 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D618077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820