Protein Alignment ras and impdh2

DIOPT Version :9

• Sequence 1: NP_001356940.1
• Gene: ras / 43873
• FlyBaseID: FBgn0003204
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_012816386.1
• Gene: impdh2 / 493428
• XenbaseID: XB-GENE-478728
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 343/527 - (65%)
• Similarity: 418/527 - (79%)
• Gaps: 31/527 - (5%)

  Fly    38 DGLSCKELFQNGEGLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAI 102
            |||:.::||..|:||||||||||||||||||::|||:|.|||.:||:.|:||||||||||:.|||
 Frog    16 DGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTEASMAI 80

  Fly   103 AMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVT 167
            ||||.|||||:|||||||:||.||.|||||:.||:.||.|:||.:.|.||.||:.::||.|.|:|
 Frog    81 AMALTGGIGIMHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHRVRDVFEAKARHGFCGIPIT 145

  Fly   168 ENGKLGGKLLGMVTSRDIDF-RENQPEVLLADIMT--TELVTAPNGINLPTANAILEKSKKGKLP 229
            ||||:|.||.|:::|||||| :..:.::.|::|||  .:||.||.|:.|..||.||::|||||||
 Frog   146 ENGKMGSKLAGIISSRDIDFLKSEEHDLALSEIMTRREDLVVAPAGVTLKEANEILQRSKKGKLP 210

  Fly   230 IVNQAGELVAMIARTDLKKARSYPNASKDSNKQLLVGAAIGTRSEDKARLALLVANGVDVIILDS 294
            |||...||||:||||||||.|.||.||||:.||||.||||||..:||.||.|||..|||.::|||
 Frog   211 IVNGNDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLVQAGVDAVVLDS 275

  Fly   295 SQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQE----- 354
            |||||::|:.|||:|||.|.:||||.|||||.||||||||||.|.|||||||||||||||
 Frog   276 SQGNSIFQINMIKFIKEKYQDLQVIAGNVVTAAQAKNLIDAGADALRVGMGSGSICITQEAAPLI 340

  Fly   355 -------------------VMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGA 400
                               ::|||.|||||||:||.|||:||||||||||||::|||.||:||||
 Frog   341 PPDLKSHSPKCPSIVTGTYMLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAKALALGA 405

  Fly   401 SAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQG 465
            |.||||||||.|:|||||||||||:|||||||||||:||:    |..:..:.|.:|.||:|||||
 Frog   406 STVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMD----KNVSSQKRYFSEADKIKVAQG 466

  Fly   466 VSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLF 530
            |||::.||||:.:::|||..|:|||||||||.|:.::|.|:|:|:|:|.|||.|||:||.||||.
 Frog   467 VSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTMSAQVEGGVHGLH 531

  Fly   531 SYEKRLF 537
            |||||||
 Frog   532 SYEKRLF 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ras	NP_001356940.1	PTZ00314	38..533	CDD:240355	337/521 (65%)
impdh2	XP_012816386.1	PTZ00314	16..534	CDD:240355	337/521 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	668	1.000	Domainoid score	I146
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	699	1.000	Inparanoid score	I658
OMA	1	1.010	-	-		QHG62889
OrthoDB	1	1.010	-	-		D281746at33208
OrthoFinder	1	1.000	-	-		FOG0001014
OrthoInspector	1	1.000	-	-		otm48426
Panther	1	1.100	-	-	LDO	PTHR11911
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R605
SonicParanoid	1	1.000	-	-		X605
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.200