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Protein Alignment ras and GMPR

DIOPT Version :9

Sequence 1:	NP_001356940.1	Gene:	ras / 43873	FlyBaseID:	FBgn0003204	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_006868.3	Gene:	GMPR / 2766	HGNCID:	4376	Length:	345	Species:	Homo sapiens

Alignment Length:	475	Identity:	113/475 - (23%)
Similarity:	169/475 - (35%)	Gaps:	157/475 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 DAELQDGLSCKELFQNGEGLTYNDFLILPGYIDFTAE-EVDLSSPLT----KSLTLRAPLVSSPM 92
            ||:|:              |.:.|.|:.|......:. ||||....|    |......|::.:.|
Human     5 DADLK--------------LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANM 55

  Fly    93 DTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARR 157
            |||...|||..|:.......||                  ||..:.|
Human    56 DTVGTFEMAAVMSQHSMFTAIH------------------KHYSLDD------------------ 84

  Fly   158 KNGFTGYPVTENGKLGGKLLGMVTSRDIDFRENQPEVLLADIMTTELVTAPNGINLPTANAILEK 222
                            .||          |..|.||.|     ....|::.:|.|
Human    85 ----------------WKL----------FATNHPECL-----QNVAVSSGSGQN---------- 108

  Fly   223 SKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDSNKQLLVGAAIGTRSEDKARLALLVANGV 287
                                  ||:|..|...|...                            |
Human   109 ----------------------DLEKMTSILEAVPQ----------------------------V 123

  Fly   288 DVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICIT 352
            ..|.||.:.|.|.:.||.:|.::..:||..::.|||||....:.||.:|.|.::||:|.||:|.|
Human   124 KFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTT 188

  Fly   353 QEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPG 417
            :.....|.||.:||.:.:..|......:|:|||....|.:.||...||..||:|.:.:|.:|..|
Human   189 RTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAG 253

  Fly   418 EYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPY 482
            |.|..:|.:||.:.||.|..||.: .|.|.|          :.:.::|.:..:..||.|...:..
Human   254 EVFERNGRKLKLFYGMSSDTAMNK-HAGGVA----------EYRASEGKTVEVPYKGDVENTILD 307

  Fly   483 LECGLQHSCQDIGANSINKL 502
            :..||:.:|..:||..:.:|
Human   308 ILGGLRSTCTYVGAAKLKEL 327

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.