DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppn and SPINT1

DIOPT Version :9

Sequence 1:NP_788752.2 Gene:Ppn / 43872 FlyBaseID:FBgn0003137 Length:2898 Species:Drosophila melanogaster
Sequence 2:NP_001373802.1 Gene:SPINT1 / 6692 HGNCID:11246 Length:529 Species:Homo sapiens


Alignment Length:230 Identity:68/230 - (29%)
Similarity:92/230 - (40%) Gaps:73/230 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1713 SLEQCQGTCAASENLPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACN 1777
            |.:|.:..|.||..:         |.|.|:|.|||||....||:.|.||||.||||||..|..|.
Human   242 STKQTEDYCLASNKV---------GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECI 297

  Fly  1778 YNCR--QPGVLKDRCAL--------------PKQTGDCSEKLAKWHFSESEKRCVPFYYSGCGGN 1826
            ..||  |.|.|:.....              |..:|.|         ..::.||    .:||   
Human   298 LACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTC---------QPTQFRC----SNGC--- 346

  Fly  1827 KNNFPTLES---CED--HCPRQVAKDICE-------------IPAEVGECANY---------VTS 1864
                 .::|   |:|  :||....:..||             .|::.|.|.:.         :..
Human   347 -----CIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPR 406

  Fly  1865 WYYDTQDQACRQFYYGGCGGNENRFPTEESCLARC 1899
            |||:...:.|.:|.||||.||:|.|..|:.||..|
Human   407 WYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 441

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpnNP_788752.2 TSP1 60..111 CDD:214559
ADAM_spacer1 214..329 CDD:283607
TSP1 468..521 CDD:214559
TSP_1 645..693 CDD:278517
Kunitz_BPTI 1611..1663 CDD:278443
Kunitz_BPTI 1670..1721 CDD:278443 2/7 (29%)
Kunitz_BPTI 1729..1781 CDD:278443 24/51 (47%)
Kunitz_BPTI 1789..1840 CDD:278443 10/69 (14%)
Kunitz_BPTI 1848..1899 CDD:278443 21/72 (29%)
KU 1920..1973 CDD:238057
Kunitz_BPTI 2001..2051 CDD:278443
KU 2071..2121 CDD:238057
Kunitz_BPTI 2127..2178 CDD:278443
KU 2192..2245 CDD:238057
KU 2251..2304 CDD:238057
KU 2316..2372 CDD:238057
WAP 2457..2497 CDD:278522
Ig 2521..2610 CDD:299845
IG_like 2530..2610 CDD:214653
IG_like 2627..2703 CDD:214653
Ig 2636..2701 CDD:143165
IG_like 2766..2841 CDD:214653
Ig 2768..2830 CDD:299845
PLAC 2851..2883 CDD:285849
SPINT1NP_001373802.1 MANEC 50..139 CDD:400058
Kunitz_BPTI 249..301 CDD:394972 27/60 (45%)
LDLa 334..366 CDD:197566 10/52 (19%)
Kunitz_BPTI 391..442 CDD:394972 18/51 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 66 1.000 Domainoid score I9914
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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