| Sequence 1: | NP_788752.2 | Gene: | Ppn / 43872 | FlyBaseID: | FBgn0003137 | Length: | 2898 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_071920.1 | Gene: | HHIP / 64399 | HGNCID: | 14866 | Length: | 700 | Species: | Homo sapiens |
| Alignment Length: | 727 | Identity: | 135/727 - (18%) |
|---|---|---|---|
| Similarity: | 218/727 - (29%) | Gaps: | 275/727 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1959 GNRFETENDCQQRCLSQEPPAPTPPRAPAPTRQPDPA-----------PTVAQCSQPADPGQCDK 2012
Fly 2013 WALHWNYNETEGRCQSFYYG-----GCGGNDNRFATEEECSARCSVNIDIRIGADPVEHDTSKCF 2072
Fly 2073 LAFE---PGNCYNNVTRWFY-----------NSAE-----------GLC-DEFVYTGCGGNANNY 2111
Fly 2112 ATEEECQNECNDAQTT------CALPPVRG--------RCSDLSRRWYFDERSG----------- 2151
Fly 2152 ------ECHEFEFTGCRG-----------------NRNNFVS-QSDCLNFCIGE-----PVVEPS 2187
Fly 2188 APTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGN-------------GNRFETRDQ 2239
Fly 2240 CERQCG--EFKG--------VDVCNEPVTTGPCTDWQTKYYFNTASQACEPFTYG----GCDGTG 2290
Fly 2291 NRFSDL-FECQTVCLAGREPRVGSAKEICLLPVATGR--------------CNGPSVHERRWYYD 2340
Fly 2341 DEAGNCVSFIYAGCS----------GNQN-NFRSFE--ACTNQCRPEP----------------- 2375
Fly 2376 -NKQDNEIGQ--------NPCDTFDAECQEL---RCPYGVRRVAARSQP------ECTQCICENP 2422
Fly 2423 CEGYSCPEGQQCAIDVASSDDRQFAPVCRDIYKPGECPALSANASGCARECYTDADCRGDNKC-C 2486
Fly 2487 SDG-----CGQL 2493 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ppn | NP_788752.2 | TSP1 | 60..111 | CDD:214559 | |
| ADAM_spacer1 | 214..329 | CDD:283607 | |||
| TSP1 | 468..521 | CDD:214559 | |||
| TSP_1 | 645..693 | CDD:278517 | |||
| Kunitz_BPTI | 1611..1663 | CDD:278443 | |||
| Kunitz_BPTI | 1670..1721 | CDD:278443 | |||
| Kunitz_BPTI | 1729..1781 | CDD:278443 | |||
| Kunitz_BPTI | 1789..1840 | CDD:278443 | |||
| Kunitz_BPTI | 1848..1899 | CDD:278443 | |||
| KU | 1920..1973 | CDD:238057 | 4/13 (31%) | ||
| Kunitz_BPTI | 2001..2051 | CDD:278443 | 10/54 (19%) | ||
| KU | 2071..2121 | CDD:238057 | 15/75 (20%) | ||
| Kunitz_BPTI | 2127..2178 | CDD:278443 | 14/99 (14%) | ||
| KU | 2192..2245 | CDD:238057 | 12/65 (18%) | ||
| KU | 2251..2304 | CDD:238057 | 12/57 (21%) | ||
| KU | 2316..2372 | CDD:238057 | 16/82 (20%) | ||
| WAP | 2457..2497 | CDD:278522 | 10/43 (23%) | ||
| Ig | 2521..2610 | CDD:299845 | |||
| IG_like | 2530..2610 | CDD:214653 | |||
| IG_like | 2627..2703 | CDD:214653 | |||
| Ig | 2636..2701 | CDD:143165 | |||
| IG_like | 2766..2841 | CDD:214653 | |||
| Ig | 2768..2830 | CDD:299845 | |||
| PLAC | 2851..2883 | CDD:285849 | |||
| HHIP | NP_071920.1 | Folate_rec | 38..220 | CDD:281076 | 37/206 (18%) |
| GSDH | 226..>428 | CDD:285269 | 41/218 (19%) | ||
| Interaction with SHH zinc binding site | 376..388 | 3/11 (27%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4295 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||