Protein Alignment Ppn and adamts16

DIOPT Version :10

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: XP_001922446.4
• Gene: adamts16 / 568792
• ZFINID: ZDB-GENE-130530-760
• Length: 1224
• Species: Danio rerio
• Alignment Length: 689
• Identity: 224/689 - (32%)
• Similarity: 325/689 - (47%)
• Gaps: 110/689 - (15%)

  Fly    45 ESSVTPGGEGN--DPD---------------------EWTPWSSPSDCSRTCGGGVSYQTRECLR 86
            |:...|..||:  .|:                     :|:.||..|.|||:|..||:::.|.|..
Zfish   570 ETKFMPAAEGSACGPEMWCRGGQCVKQADAGPKAVDGQWSTWSGWSSCSRSCESGVTHRDRVCSS 634

  Fly    87 -RDDRGEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCSRFDRQQFDGVFYEWVPYTNAPNP--CE 148
             |...|...|.|.||.|..|||.|||....||||.||:.|:.:.|.|.:|:|.|||...:.  |:
Zfish   635 PRPAHGGRFCEGSSRSYKLCNTDDCPANAVDFRAAQCAEFNSKPFRGWYYKWRPYTRVDDQDVCK 699

  Fly   149 LNCMPKGERFYYRQREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTC 213
            |.|:.:|..|::....||.|||.|.....|||::|.|..||||.:|||:|..|.|..|.||.|||
Zfish   700 LYCLAEGYDFFFALSSKVRDGTLCAQDSTDVCIDGICEKVGCDRVLGSNAVPDMCGVCKGDNSTC 764

  Fly   214 KTIRNTITTKDLAPGYNDLLLLPEGATNIRIEETVPSSNYLACRNHSGHYYLNGDWRIDFPRPMF 278
            |..:...:.:.....|..::.:|.||.:||:.|...||:|||.||....|||||.|.:|:|....
Zfish   765 KIYKGQYSKQHHLSQYYRVVTIPAGARSIRVSELNSSSSYLALRNLQRKYYLNGAWTVDWPGRHS 829

  Fly   279 FANSWWNYQRKPMGFAAPDQLTCSGPISESLFIVMLVQEKNISLDYEYSIPESLSHSQQDTHTWT 343
            .|.:.::|:|.   :..|:.|:.|||.:::|.|.:|:|..|..:.:||    :|:..|:..::|.
Zfish   830 IAGAIFDYKRP---YNRPESLSSSGPTNQTLVIEVLLQGWNPGVQWEY----TLNREQKHNYSWA 887

  Fly   344 HHQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVE-EQACGTEPCAPHWVEGEWSK 407
            ..: :.||:||.||....|..|...:.. :||.|.|..:|:|.. ..:|.|:||...|...:||.
Zfish   888 VVR-SQCSSSCAGGQMVSKSICYRDLRF-QVNSSYCSARSRPSSGVMSCNTQPCPASWSVQDWSS 950

  Fly   408 CSKGCGSDGFQNRSITCERISSSGEHTVE--EDAVCLKEVGNKPATKQECNRDVKNC-PKYHLGP 469
            ||:.||| |.|.|.:.|  :..:|...:|  .||.|.:..   ||....||  ..:| |.:..|.
Zfish   951 CSRSCGS-GQQVRRVVC--VQKTGPDQLETVADAQCPQPA---PAHTHSCN--THSCPPAWSAGA 1007

  Fly   470 WTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVE-EKPETEKSCLLTPCEGVDWIISQWSGC 533
            ||.|.:.||.|...|.|.|.: .||  .|||:..|.: .||..::.|.:..|
Zfish  1008 WTQCSRKCGKGVMKRPVLCVL-SNG--VVLPDSSCADLLKPSVQEICFIKHC------------- 1056

  Fly   534 NACGQNTETRTAICGNKEGKVYPEEFCEPEVPTLSRPCKSPKCEAQWFSSEWSKCSAPCGKGVKS 598
                           .|:.|                        ||||.|.|:.||..||:|::.
Zfish  1057 ---------------RKQRK------------------------AQWFVSTWTPCSVSCGEGLQQ 1082

  Fly   599 RIVICGEFDGKTVTPADDDSKCNKETKP--ESEQDCEGEEKVCPG---EWFTGPWGKCSKPCGGG 658
            |:|.|.|.|...........||...::|  :.::.|...|  ||.   .|::.||.:|:..||||
Zfish  1083 RVVKCAEKDYSGKYRELSQKKCQHVSRPSVDLQRVCVQAE--CPAAGTHWYSSPWSQCTVSCGGG 1145

  Fly   659 ERVREVLCLSNGTKSVNCDEEKVEPLSEKCNSEACTEDE 697
            .::|.|.|||.|..|..|..:....:|:.||:..|.:.|
Zfish  1146 VQIRSVQCLSLGRPSSGCVLQMKPLMSQACNTAFCPQPE 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	23/51 (45%)
		ADAMTS_CR_3	116..213	CDD:437068	44/98 (45%)
		ADAMTS_spacer1	222..329	CDD:461796	37/106 (35%)
		TSP1_ADAMTS	347..396	CDD:465950	16/49 (33%)
		TSP1_ADAMTS	400..457	CDD:465950	20/58 (34%)
		TSP1_ADAMTS	465..520	CDD:465950	19/55 (35%)
		TSP1_ADAMTS	580..632	CDD:465950	17/53 (32%)
		TSP1_ADAMTS	643..693	CDD:465950	19/49 (39%)
		MSCRAMM_ClfA	<1049..1262	CDD:468110
		Kunitz_papilin_lacunin-like	1612..1663	CDD:438681
		Kunitz_BPTI	1670..1721	CDD:425421
		Kunitz-type	1730..1780	CDD:438633
		Kunitz_BPTI	1789..1840	CDD:425421
		Kunitz_papilin_mig6-like	1849..1899	CDD:438679
		Kunitz_papilin_mig6-like	1922..1972	CDD:438679
		Kunitz_papilin_mig6-like	2001..2051	CDD:438679
		Kunitz-type	2071..2121	CDD:438633
		Kunitz_BPTI	2127..2178	CDD:425421
		Kunitz_BPTI	2193..2245	CDD:425421
		Kunitz_BPTI	2252..2303	CDD:425421
		Kunitz_BPTI	2317..2372	CDD:425421
		WAP	2455..2497	CDD:459672
		Ig	2530..2610	CDD:472250
		Ig strand B	2539..2543	CDD:409353
		Ig strand C	2552..2556	CDD:409353
		Ig strand E	2576..2579	CDD:409353
		Ig strand F	2589..2594	CDD:409353
		Ig strand G	2603..2606	CDD:409353
		IG_like	2627..2703	CDD:214653
		Ig strand B	2636..2640	CDD:409353
		Ig strand C	2649..2653	CDD:409353
		Ig strand E	2670..2674	CDD:409353
		Ig strand F	2684..2689	CDD:409353
		Ig strand G	2697..2700	CDD:409353
		I-set	2766..2845	CDD:400151
		Ig strand B	2771..2775	CDD:409353
		Ig strand C	2784..2788	CDD:409353
		Ig strand F	2821..2826	CDD:409353
		PLAC	2851..2883	CDD:462560
adamts16	XP_001922446.4	None