Protein Alignment Ppn and adamts9

DIOPT Version :9

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: NP_001361725.1
• Gene: adamts9 / 493280
• XenbaseID: XB-GENE-1013537
• Length: 1923
• Species: Xenopus tropicalis
• Alignment Length: 852
• Identity: 241/852 - (28%)
• Similarity: 350/852 - (41%)
• Gaps: 228/852 - (26%)

  Fly    36 QYGANMYLPESSVTPGGEGNDPDEWTPWSSPSDCSRTCGGGVSYQTRECLRRDDR-GEAVCSGGS 99
            :||  :.:|:.......:|:    |..||....|||:||||:....|||.|.:.: |...|.|..
 Frog   558 RYG--VCIPKERDVQIADGS----WGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRR 616

  Fly   100 RRYFSCNTQDCPEEESDFRAQQCSRFDRQQF--DGV--FYEWVP-YTN--APNPCELNCMPKGER 157
            .::.||||:.|.:.:.|||.:||:.||.:.|  :|:  ...||| |:.  ..:.|:|.|...|..
 Frog   617 MKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGST 681

  Fly   158 FYYRQREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITT 222
            .||:.|::|||||.|.....|:||.|.|...|||.:|.|.|:.|||..||||.|:||||..|...
 Frog   682 AYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYNI 746

  Fly   223 KDLAPGYNDLLLLPEGATNIRIEETVPS-----SNYLACRNHSGHYYLNGDWRID-FPRPMFFAN 281
              :..|||.::.:|.||||:.:.:...|     .||||..|..|.:.||||:.:. |.|.:...|
 Frog   747 --VHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGN 809

  Fly   282 S------------------------------------------------------WWN------- 285
            :                                                      :||
 Frog   810 AVIEYSGSDNAIERINCTDRIEQEIVLQILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQP 874

  Fly   286 --------YQRKPMGFAAPDQLTCSG----------PISESLFIVMLVQ---------------- 316
                    .::||:.....|||..|.          |::|.......|:
 Frog   875 CNKMCQGERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRWHVARKSECTVQCGLG 939

  Fly   317 ---------------EKNISLDYEYSIPESLSHSQQ-----------DTHTWTHHQFNACSASCG 355
                           .||..:|..|     .||.|:           :|..|.:..::.||.|||
 Frog   940 YRTLDIHCAKYTRADGKNEKVDERY-----CSHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCG 999

  Fly   356 GGSQSRKVTCNNRITLAEV-NPSLCDQKSKPVEEQACGTEPCAPHWVEGEWSKCSKGCGSDGFQN 419
            .|::.|:..|.|  .|.:: :.|.|.|:.||. ||.|...|| |.|..|:||.|...||. |.::
 Frog  1000 TGTRRRRAICVN--ALHDILDDSKCGQQEKPT-EQRCSEFPC-PQWKTGDWSDCLVTCGK-GHKH 1059

  Fly   420 RSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNCPKYHLGPWTPCDKLCGDGKQTR 484
            |...|:    .|:..: .|..|  :...||.:.:.|.:  ..|..:.:|||..|...||.|.|.|
 Frog  1060 RQTWCQ----FGDDRL-HDRFC--DTETKPESVEACEQ--PECASWQVGPWGQCTAACGPGYQMR 1115

  Fly   485 KVTCFIEENGHKRVLPEEDC-VEEKPETEKSCLLTPCEGV-----------DWIISQWSGCNA-C 536
            .|.|.:  ..::.|:.:.:| ...:|...:.|....|.|:           .|....|:.|:| |
 Frog  1116 VVKCVV--GAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATC 1178

  Fly   537 GQNTETRTAICGNKEGKVYPEEFCE--PEVPTLSRPCKSPKCEAQWFSSEWSKCSAPCGKGVKSR 599
            |:.|..|...|.:.:|.|..|..|.  |: |..:..|....| .||.:.|||.||..||:|..:|
 Frog  1179 GKGTRMRYVSCRDDQGSVADEAACAQLPK-PLATEACSVTPC-GQWKALEWSSCSVTCGQGKATR 1241

  Fly   600 IVICGEFDGKTVTPADDDSKCNKETKPESEQDCE------------------------------- 633
            .|||.:|..:||    |.|:|:.:..|..||:|.
 Frog  1242 QVICVDFADQTV----DGSECDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTL 1302

  Fly   634 -------GEEKVCPG-EWFTGPWGKCSKPCGGGERVREVLCL-SNGTKSVNCDEEKVEPLSEK-C 688
                   |......| :|.|||||.||..|.||.:.|.|:|. .||..:.||| ||.:|:.:: |
 Frog  1303 AILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPASNCD-EKTKPIEQRSC 1366

  Fly   689 NSEACTE 695
            .|.:|.:
 Frog  1367 ESGSCPQ 1373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	21/51 (41%)
		ADAM_spacer1	214..329	CDD:283607	41/230 (18%)
		TSP1	468..521	CDD:214559	15/53 (28%)
		TSP_1	645..693	CDD:278517	23/49 (47%)
		Kunitz_BPTI	1611..1663	CDD:278443
		Kunitz_BPTI	1670..1721	CDD:278443
		Kunitz_BPTI	1729..1781	CDD:278443
		Kunitz_BPTI	1789..1840	CDD:278443
		Kunitz_BPTI	1848..1899	CDD:278443
		KU	1920..1973	CDD:238057
		Kunitz_BPTI	2001..2051	CDD:278443
		KU	2071..2121	CDD:238057
		Kunitz_BPTI	2127..2178	CDD:278443
		KU	2192..2245	CDD:238057
		KU	2251..2304	CDD:238057
		KU	2316..2372	CDD:238057
		WAP	2457..2497	CDD:278522
		Ig	2521..2610	CDD:299845
		IG_like	2530..2610	CDD:214653
		IG_like	2627..2703	CDD:214653
		Ig	2636..2701	CDD:143165
		IG_like	2766..2841	CDD:214653
		Ig	2768..2830	CDD:299845
		PLAC	2851..2883	CDD:285849
adamts9	NP_001361725.1	Pep_M12B_propep	44..192	CDD:366707
		ZnMc_ADAMTS_like	274..480	CDD:239801
		ADAM_CR_2	495..563	CDD:375321	2/6 (33%)
		TSP1	576..627	CDD:214559	21/50 (42%)
		ADAM_spacer1	738..856	CDD:368694	26/119 (22%)
		TSP1	986..1039	CDD:214559	21/56 (38%)
		TSP1	1041..1093	CDD:214559	16/61 (26%)
		TSP1	1096..1151	CDD:214559	15/56 (27%)
		TSP1	1166..1219	CDD:214559	16/53 (30%)
		TSP1	1219..1275	CDD:214559	25/60 (42%)
		TSP1	1320..1372	CDD:214559	24/52 (46%)
		TSP1	1374..1428	CDD:214559	241/852 (28%)
		PTZ00441	<1467..>1531	CDD:240420
		TSP1	1550..1601	CDD:214559
		TSP1	1604..1664	CDD:214559
		GON	1726..1922	CDD:370060

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11832
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000