Protein Alignment Ppn and Adamts20

DIOPT Version :9

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: XP_038936261.1
• Gene: Adamts20 / 315263
• RGDID: 1307725
• Length: 1928
• Species: Rattus norvegicus
• Alignment Length: 902
• Identity: 244/902 - (27%)
• Similarity: 347/902 - (38%)
• Gaps: 259/902 - (28%)

  Fly     5 RRL-CSTALVAFIVLASIH-----------DSQSRFPGLRQKRQYGANMYLPESSVTPGGEGNDP 57
            ||| |::|       ..:|           |..|..||:...|..         .||...|....
  Rat   506 RRLWCTSA-------EGVHKGCRTQHMPLADGTSCGPGMHCHRGL---------CVTRDMETRPV 554

  Fly    58 D-EWTPWSSPSDCSRTCGGGVSYQTRECLRRDDR-GEAVCSGGSRRYFSCNTQDCPEEESDFRAQ 120
            | ||.||...|.||||||||:....|.|.|.:.| |...|.|...::.||||..||:.:.|||.:
  Rat   555 DGEWGPWGPYSSCSRTCGGGIRSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREK 619

  Fly   121 QCSRFDRQQFD--GV--FYEWVP-YTN--APNPCELNCMPKGERFYYRQREKVVDGTRCNDKDLD 178
            |||.||.:.||  |:  ...|:| |:.  ..:.|:|.|...|...:|:.:::|.|||.|..:..|
  Rat   620 QCSDFDGKHFDISGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETND 684

  Fly   179 VCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATNIR 243
            :||.|.|...|||.:|.|.||.|||..||||.|:|:|:.....:...  |||.::.:|.|||||.
  Rat   685 ICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHY--GYNVVVKIPAGATNIE 747

  Fly   244 IEETVPS-----SNYLACRNHSGHYYLNGDWRIDF------------------------------ 273
            |.:...|     .||||..:..|::.|||::.:..
  Rat   748 ILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERINSTDRL 812

  Fly   274 ----------------PRPMFFAN----------SW-----WN---------YQRKPMGFAAPDQ 298
                            |...:..|          ||     |.         ::||.......|:
  Rat   813 EAELVLQVLCVGNLYNPDVHYIFNIPIEERSNLFSWDPYGPWQDCTKMCQGLHRRKIACIRKSDR 877

  Fly   299 LTCSGPISESLFIVMLVQEK-NISLDYEYSIPESLSHSQQ--------DTH-------------- 340
            ...|......|.:.:.|.|: |...:..:.|......|.|        |.|
  Rat   878 AVVSDQSCSHLPLPLFVTERCNTDCELRWHITGKSDCSSQCGQGYRTLDVHCMKYSVHKGQTVPV 942

  Fly   341 ------------------------TWTHHQFNACSASCGGGSQSRKVTCNNRI--TLAEVNPSLC 379
                                    .|.:.:::.||.|||||.::|:..|.|..  .|||..   |
  Rat   943 GDQYCGDQLKPPNREPCHGSCVLTRWHYSEWSQCSRSCGGGEKTRESYCVNGFGHRLAERE---C 1004

  Fly   380 DQKSKPVEEQACGTEPCAPHWVEGEWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKE 444
            .:..:.|... |...|| |.|...|||:|...||. |.:.|.:.|:|    .|..|.:| .|  :
  Rat  1005 QELPRVVLGN-CNDFPC-PGWATSEWSECPVTCGK-GMKQRQVWCQR----SEDPVGDD-FC--D 1059

  Fly   445 VGNKPATKQECNRDVKNCPKYHLGPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVE-EK 508
            ...||.:...|  :::.|..:|:|||..|...||.|.|.|.|.|..|..|  .||.:.:|.. .:
  Rat  1060 ASTKPESLGPC--ELRACASWHVGPWGSCTVTCGHGYQVRAVKCVSEILG--TVLDDRECPRASR 1120

  Fly   509 PETEKSCLLTPC-----------------EGVDWIISQWSGCN-ACGQNTETRTAICGNKEGKVY 555
            |...:.|:..||                 :...|....|:.|: :||:.::.|...|.:....|.
  Rat  1121 PSDRQDCIFAPCLAILKVGATSLPAIPLGKAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDGVA 1185

  Fly   556 PEEFCEPEVPTLSRP-----CKSPKCEAQWFSSEWSKCSAPCGKGVKSRIVICGEFDGKTVTPAD 615
            .|..|    ..|.||     |.|| | .:|.:.:||.|||.||.|..:|.|:|..:....
  Rat  1186 DELNC----AHLPRPAEVSLCFSP-C-GEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLV----- 1239

  Fly   616 DDSKCNKETKPESEQDCEGEEKVCP---------------------------------------- 640
            |:|.|:.|.:|.:||:|  ....||
  Rat  1240 DESYCDPEGRPVTEQEC--RLAACPPSYSRSPSSSEQPSHGPGRNVPLTHKPEENPDQGVQLSIR 1302

  Fly   641 -GEWFTGPWGKCSKPCGGGERVREVLCL-SNGTKSVNCDEEKVEPLSEKCNSEACTE 695
             .:|.|||||.||:.|.||.:.|.|:|. .:|..:.:|:.....|.|:.|.|..|.:
  Rat  1303 GNQWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSATSCEATSKPPESKHCGSGPCPQ 1359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	23/51 (45%)
		ADAM_spacer1	214..329	CDD:283607	33/190 (17%)
		TSP1	468..521	CDD:214559	20/70 (29%)
		TSP_1	645..693	CDD:278517	19/48 (40%)
		Kunitz_BPTI	1611..1663	CDD:278443
		Kunitz_BPTI	1670..1721	CDD:278443
		Kunitz_BPTI	1729..1781	CDD:278443
		Kunitz_BPTI	1789..1840	CDD:278443
		Kunitz_BPTI	1848..1899	CDD:278443
		KU	1920..1973	CDD:238057
		Kunitz_BPTI	2001..2051	CDD:278443
		KU	2071..2121	CDD:238057
		Kunitz_BPTI	2127..2178	CDD:278443
		KU	2192..2245	CDD:238057
		KU	2251..2304	CDD:238057
		KU	2316..2372	CDD:238057
		WAP	2457..2497	CDD:278522
		Ig	2521..2610	CDD:299845
		IG_like	2530..2610	CDD:214653
		IG_like	2627..2703	CDD:214653
		Ig	2636..2701	CDD:143165
		IG_like	2766..2841	CDD:214653
		Ig	2768..2830	CDD:299845
		PLAC	2851..2883	CDD:285849
Adamts20	XP_038936261.1	Pep_M12B_propep	41..186	CDD:396235
		ZnMc_ADAMTS_like	257..463	CDD:239801
		ADAM_CR_2	478..545	CDD:407643	11/54 (20%)
		TSP1	558..610	CDD:214559	23/51 (45%)
		ADAM_spacer1	720..838	CDD:368694	22/119 (18%)
		TSP1_ADAMTS	906..959	CDD:408800	5/52 (10%)
		TSP1_ADAMTS	968..1020	CDD:408800	17/55 (31%)
		TSP1_ADAMTS	1023..1075	CDD:408800	18/61 (30%)
		TSP1_ADAMTS	1078..1132	CDD:408800	19/55 (35%)
		TSP1_ADAMTS	1154..1206	CDD:408800	16/56 (29%)
		TSP1_ADAMTS	1209..1261	CDD:408800	20/58 (34%)
		TSP1_ADAMTS	1306..1357	CDD:408800	20/50 (40%)
		TSP1_ADAMTS	1360..1412	CDD:408800	244/902 (27%)
		TSP1_ADAMTS	1418..1471	CDD:408800
		TSP1_ADAMTS	1474..1527	CDD:408800
		TSP1_ADAMTS	1532..1585	CDD:408800
		TSP1_ADAMTS	1657..1708	CDD:408800
		GON	1713..1880	CDD:400843

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910