Protein Alignment Ppn and AdamTS-B

DIOPT Version :10

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: NP_572247.2
• Gene: AdamTS-B / 31490
• FlyBaseID: FBgn0029791
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 450
• Identity: 154/450 - (34%)
• Similarity: 215/450 - (47%)
• Gaps: 49/450 - (10%)

  Fly    36 QYGANMYLPESSVTPGGEGNDPDEWTPWSSPSDCSRTCGGGVSYQTRECLRRDD----RGEAVCS 96
            |.|..:...|.:...||       |..||..|:|||:||||||.|.|||   |:    .|...|.
  Fly   597 QNGKCVRREELAAVNGG-------WGDWSEWSECSRSCGGGVSTQQREC---DNPVPANGGVFCI 651

  Fly    97 GGSRRYFSCNTQDCPEEESDFRAQQCSRFDRQQFDGVFYEWVPYTNAPNPCELNCMPKGERFYYR 161
            |..:||..|..:.||.||..||||||:|||...:.|..|:|:|:.:..|||:|.|....:.....
  Fly   652 GERKRYKICRKRPCPAEEPSFRAQQCARFDNVSYQGATYKWLPFFDKNNPCKLFCSDVDDTIIAN 716

  Fly   162 QREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTIT----T 222
            ....|:|||.|.....::|::|.|..||||.::.|:.::|:|..|||.|..|:.:|.|.|    .
  Fly   717 WGATVLDGTPCTLGTNNMCIDGICKKVGCDWIVDSEVQDDRCGVCGGSGDQCQPVRETYTDPFAA 781

  Fly   223 KDLAPGYNDLLLLPEGATNIRIEETVPSSNYLACRNHSG--HYYLNGDWRIDFPRPMFFANSWWN 285
            ||.|  |.:::.:|..|.:|.|.|...|.::||.....|  .:|||||..|..|.....|.:...
  Fly   782 KDGA--YVEIVTIPARARHILIRELANSPHFLAIATGDGGDRFYLNGDSLISMPGEFEIAGAESL 844

  Fly   286 YQRKPMGFAAPDQLTCSGPISESLFIVMLVQ--EKNISLDYEYSIPESLSHSQQDTHTWTHHQFN 348
            |.|    ....:.:|...||..|:.:..:|:  |.|..:.||:::| :|:.:......|....:.
  Fly   845 YDR----VDEQETITIPQPIQHSISLYAIVRGNESNAGIFYEFTLP-ALNVTAGRQFQWRLSNWT 904

  Fly   349 ACSASCGGGSQSRKVTC-NNRITLAEVNPSLCDQKSKPVEEQA--CGTEPCAPHWVEGEWSKCSK 410
            |||||||||.|.|:..| .|...|.:..|.....|:|....|:  ||.:||..||..|.|..|..
  Fly   905 ACSASCGGGVQHREPICQENGKALGDTLPCWTHAKNKRPARQSRGCGDQPCPAHWWPGPWQFCPV 969

  Fly   411 GCGSDGF-----QNRSITCERISSSGEH-TVEEDAVCLKEVGN--KPATKQECNRDVKNC 462
            .|...||     :.||:.|     ..|| .|..||.|    |:  |||..:.|...:..|
  Fly   970 TCRPVGFVAPPQRRRSVVC-----LDEHDVVVADAEC----GHLQKPAEMEPCESSLPIC 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	24/54 (44%)
		ADAMTS_CR_3	116..213	CDD:437068	37/96 (39%)
		ADAMTS_spacer1	222..329	CDD:461796	32/110 (29%)
		TSP1_ADAMTS	347..396	CDD:465950	20/51 (39%)
		TSP1_ADAMTS	400..457	CDD:465950	21/64 (33%)
		TSP1_ADAMTS	465..520	CDD:465950
		TSP1_ADAMTS	580..632	CDD:465950
		TSP1_ADAMTS	643..693	CDD:465950
		MSCRAMM_ClfA	<1049..1262	CDD:468110
		Kunitz_papilin_lacunin-like	1612..1663	CDD:438681
		Kunitz_BPTI	1670..1721	CDD:425421
		Kunitz-type	1730..1780	CDD:438633
		Kunitz_BPTI	1789..1840	CDD:425421
		Kunitz_papilin_mig6-like	1849..1899	CDD:438679
		Kunitz_papilin_mig6-like	1922..1972	CDD:438679
		Kunitz_papilin_mig6-like	2001..2051	CDD:438679
		Kunitz-type	2071..2121	CDD:438633
		Kunitz_BPTI	2127..2178	CDD:425421
		Kunitz_BPTI	2193..2245	CDD:425421
		Kunitz_BPTI	2252..2303	CDD:425421
		Kunitz_BPTI	2317..2372	CDD:425421
		WAP	2455..2497	CDD:459672
		Ig	2530..2610	CDD:472250
		Ig strand B	2539..2543	CDD:409353
		Ig strand C	2552..2556	CDD:409353
		Ig strand E	2576..2579	CDD:409353
		Ig strand F	2589..2594	CDD:409353
		Ig strand G	2603..2606	CDD:409353
		IG_like	2627..2703	CDD:214653
		Ig strand B	2636..2640	CDD:409353
		Ig strand C	2649..2653	CDD:409353
		Ig strand E	2670..2674	CDD:409353
		Ig strand F	2684..2689	CDD:409353
		Ig strand G	2697..2700	CDD:409353
		I-set	2766..2845	CDD:400151
		Ig strand B	2771..2775	CDD:409353
		Ig strand C	2784..2788	CDD:409353
		Ig strand F	2821..2826	CDD:409353
		PLAC	2851..2883	CDD:462560
AdamTS-B	NP_572247.2	Pep_M12B_propep	47..195	CDD:460254
		ZnMc_ADAMTS_like	314..518	CDD:239801
		ADAMTS_CR_2	534..602	CDD:465496	2/4 (50%)
		TSP1	614..666	CDD:214559	24/54 (44%)
		ADAMTS_CR_3	672..768	CDD:437068	37/95 (39%)
		ADAMTS_spacer1	770..886	CDD:461796	35/121 (29%)
		TSP1	901..956	CDD:214559	21/54 (39%)
		TSP1_ADAMTS	959..1020	CDD:465950	21/69 (30%)