DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppn and Vwa7

DIOPT Version :9

Sequence 1:NP_788752.2 Gene:Ppn / 43872 FlyBaseID:FBgn0003137 Length:2898 Species:Drosophila melanogaster
Sequence 2:XP_038954602.1 Gene:Vwa7 / 309611 RGDID:1303137 Length:920 Species:Rattus norvegicus


Alignment Length:447 Identity:91/447 - (20%)
Similarity:142/447 - (31%) Gaps:158/447 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly  2406 VAARSQPECTQCICENPCEGYSCPEGQQCAIDVASSDDRQFAPVCRDIYKPGECPALSANASGCA 2470
            :|....|.|:.      |||.||                           ||....|:...||..
  Rat   201 LAQVGDPTCSD------CEGLSC---------------------------PGNMMNLTMLTSGYF 232

  Fly  2471 RECYTDADCRGDNKCCSDGCGQLCVHPAR----PTQPPRTQAPVVSYPGDARAALEPKEA--HEL 2529
                      |.|.....|   .|.|..|    .:||||        .|..:.:..|..:  |.|
  Rat   233 ----------GTNPPKPPG---KCSHGGRFDQSSSQPPR--------GGINKDSTSPSFSPHHRL 276

  Fly  2530 DVQTAIGGIAVLRCFATGNPAPNITWSLKNLVINTNKGRYVLTANGDLTIVQVRQTDDGTYVCVA 2594
            .:|.|  .:|:|.             |::.|.:..::    |...|...::.:......::|...
  Rat   277 HLQAA--EVALLA-------------SIEALSLLRSR----LGTRGFSRLLDITPASSLSFVLDT 322

  Fly  2595 SNGLGEPV-------RREVALQVTEPVSQPAYIYGDKNVTQIVELNRPAVIRCPAGGF------P 2646
            :..:||.:       ||.|..:...|:...:||        :|..:.|        ||      .
  Rat   323 TGSMGEEINAAKIQARRIVEQRQGSPMEPVSYI--------LVPFHDP--------GFGPVFTTS 371

  Fly  2647 EPHVSWWRNGQMFGLKNN------LMARDYSLVFNSIQLSDLGLYT----CEVYNQRRPVSL--- 2698
            :|...|.:..::..|...      |.|.:.:|: ::..|||:.::|    .:.:...|..||   
  Rat   372 DPDSFWQKLTEIHALGGGDEPEMCLSALELALL-HTPPLSDIFVFTDASPKDAFLTNRVESLTRE 435

  Fly  2699 ---RVTL-------KAVGPVR--PLSPEE-EQYMQYVLNPATRPVTQRPSYPYRPTRPAYVPEPT 2750
               |||.       :|.|..|  .|||.. |.|....|......:..:..: .|.. .|.|.|..
  Rat   436 RRCRVTFLVTEDPSRAQGRGRREALSPSRFEPYEAIALASGGEVIFTKDQH-IRDV-AAVVGESM 498

  Fly  2751 VNVHAVLALEPKNSYTPGS-------------TIVMSCSVQGYPEPNVTWIKDDVPL 2794
            ..: ..|.|||. .:|||.             |:.|...:.|:      |||....|
  Rat   499 AGL-VTLPLEPP-IFTPGEPCVFAVDSLLSKVTVRMHGDISGF------WIKSPAGL 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpnNP_788752.2 TSP1 60..111 CDD:214559
ADAM_spacer1 214..329 CDD:283607
TSP1 468..521 CDD:214559
TSP_1 645..693 CDD:278517
Kunitz_BPTI 1611..1663 CDD:278443
Kunitz_BPTI 1670..1721 CDD:278443
Kunitz_BPTI 1729..1781 CDD:278443
Kunitz_BPTI 1789..1840 CDD:278443
Kunitz_BPTI 1848..1899 CDD:278443
KU 1920..1973 CDD:238057
Kunitz_BPTI 2001..2051 CDD:278443
KU 2071..2121 CDD:238057
Kunitz_BPTI 2127..2178 CDD:278443
KU 2192..2245 CDD:238057
KU 2251..2304 CDD:238057
KU 2316..2372 CDD:238057
WAP 2457..2497 CDD:278522 8/39 (21%)
Ig 2521..2610 CDD:299845 17/97 (18%)
IG_like 2530..2610 CDD:214653 14/86 (16%)
IG_like 2627..2703 CDD:214653 20/104 (19%)
Ig 2636..2701 CDD:143165 16/86 (19%)
IG_like 2766..2841 CDD:214653 10/42 (24%)
Ig 2768..2830 CDD:299845 8/40 (20%)
PLAC 2851..2883 CDD:285849
Vwa7XP_038954602.1 Het-C <163..>190 CDD:399889
vWFA 316..>422 CDD:412136 23/122 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4475
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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