Protein Alignment Ppn and T21B6.3

DIOPT Version :9

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: NP_509829.2
• Gene: T21B6.3 / 181284
• WormBaseID: WBGene00011880
• Length: 821
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 108/376 - (28%)
• Similarity: 154/376 - (40%)
• Gaps: 97/376 - (25%)

  Fly   340 HTWTHHQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACGTEPCAPHWVEG- 403
            |.|:  .::.||.:||.|::||:..|:..      |....|.:::|     |...||.. |.|.
 Worm   459 HDWS--DWSTCSCTCGDGAKSRRRECSTN------NCQGADYETEP-----CNLGPCQT-WSEWC 509

  Fly   404 EWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNCPKY-HL 467
            |||.||..||| |.:.|:..|.    .|.:..|          .|....::|:  ...||:: ..
 Worm   510 EWSTCSASCGS-GQRERTRFCH----LGTNRCE----------GKDYESEQCS--AGPCPEWSQW 557

  Fly   468 GPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVEEKPETE-KSCLLTPCE-GVDWIISQW 530
            ..|..|...||.|...|:.||.   .|   |..:..|  :.|:|| ::|...||. ...|  .:|
 Worm   558 EDWGQCSVTCGQGVAVRQRTCL---GG---VFGDHLC--QGPKTEQRACDGGPCSLWSPW--QEW 612

  Fly   531 SGCNA-CGQNTETRTAIC--------GNKEGKVYPEEFCEPEVPTLSRPCKSPKCEAQWFS-SEW 585
            |.|:| ||...:.|..:|        .|:|                |:.|..|.| |:|.. .||
 Worm   613 STCSASCGSGMKRRQRVCQFGTDCQGPNEE----------------SQFCYGPPC-AEWTEWCEW 660

  Fly   586 SKCSAPCGKGVKSRIVICGEFDGKTVTPADDDSKCNKETKPESEQD-CEGEEKVCPGEWFTGPWG 649
            |.||:.||.|.::|...|...:|:..|....         |..|.. |||:......||.  .|.
 Worm   661 SGCSSKCGPGQRTRTRGCLGPNGQEATTCQG---------PSIETTLCEGQSCCNWSEWC--HWS 714

  Fly   650 KCSKPCGGGERVREVLCLSNG---TKSVNCD----EEKVEPLSEKCNSEAC 693
            .|.|.||||:.:|...||::.   ..|.:||    |||      :|||::|
 Worm   715 MCDKECGGGQSIRTRTCLNSAGSPDSSCHCDGPDREEK------ECNSQSC 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559
		ADAM_spacer1	214..329	CDD:283607
		TSP1	468..521	CDD:214559	16/53 (30%)
		TSP_1	645..693	CDD:278517	19/54 (35%)
		Kunitz_BPTI	1611..1663	CDD:278443
		Kunitz_BPTI	1670..1721	CDD:278443
		Kunitz_BPTI	1729..1781	CDD:278443
		Kunitz_BPTI	1789..1840	CDD:278443
		Kunitz_BPTI	1848..1899	CDD:278443
		KU	1920..1973	CDD:238057
		Kunitz_BPTI	2001..2051	CDD:278443
		KU	2071..2121	CDD:238057
		Kunitz_BPTI	2127..2178	CDD:278443
		KU	2192..2245	CDD:238057
		KU	2251..2304	CDD:238057
		KU	2316..2372	CDD:238057
		WAP	2457..2497	CDD:278522
		Ig	2521..2610	CDD:299845
		IG_like	2530..2610	CDD:214653
		IG_like	2627..2703	CDD:214653
		Ig	2636..2701	CDD:143165
		IG_like	2766..2841	CDD:214653
		Ig	2768..2830	CDD:299845
		PLAC	2851..2883	CDD:285849
T21B6.3	NP_509829.2	PAN_AP	35..108	CDD:214680
		TSP1	458..502	CDD:214559	14/55 (25%)
		TSP1	505..552	CDD:214559	17/63 (27%)
		TSP1	554..604	CDD:214559	16/57 (28%)
		TSP1	606..651	CDD:214559	14/62 (23%)
		TSP1	654..704	CDD:214559	18/58 (31%)
		TSP1	707..759	CDD:214559	21/59 (36%)
		TSP1	765..809	CDD:214559

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810