Protein Alignment Ppn and adamts15

DIOPT Version :10

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: XP_012822382.1
• Gene: adamts15 / 100489270
• XenbaseID: XB-GENE-6051208
• Length: 938
• Species: Xenopus tropicalis
• Alignment Length: 443
• Identity: 150/443 - (33%)
• Similarity: 203/443 - (45%)
• Gaps: 64/443 - (14%)

  Fly    60 WTPWSSPSDCSRTCGGGVSYQTRECLRRD-DRGEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCS 123
            |..||....|||||||||....|||...: ..|.:.|.|...:|.||:...|||....||.:||
 Frog   520 WGKWSPYGQCSRTCGGGVQLAKRECNNPEPSNGGSFCEGLRVKYRSCSLNPCPETGKSFREEQC- 583

  Fly   124 RFDRQQFDGVFYE---------WVPYTNAPNP---CELNCMPKGERFYYRQREKVVDGTRCNDKD 176
                :.|:|..:.         |||..:..:|   |:|.|...|..::|....||||||.|:...
 Frog   584 ----ESFNGFNHSTNRITQTVGWVPKYSGVSPRDKCKLICRANGTGYFYVLSPKVVDGTPCSPDA 644

  Fly   177 LDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATN 241
            ..|||.|:|:..|||..|||..|.||||.||||..:||.| :.:.||.: .|||.::.:|.||:|
 Frog   645 TSVCVQGKCIKAGCDGQLGSKKKYDKCRVCGGDNKSCKKI-SGLFTKPI-HGYNFVVTIPAGASN 707

  Fly   242 IRIEE-----TVPSSNYLACRNHSGHYYLNGDWRIDF-PRPMFFANSWWNYQRKPMGFAAPDQLT 300
            :.:.:     .:...||||.:|..|.|.|||::.:.. .|.:....|...|....   .|.:.|.
 Frog   708 LDVRQRGYKGLINDDNYLAVKNAQGRYLLNGNYIVAAGERDISVRGSLLKYSGTG---TAVETLQ 769

  Fly   301 CSGPISESLFIVMLVQEKNI--SLDYEYSIP---------ESLSHS----------QQDTHTWTH 344
            ....|.|||.|.:|...|..  .|.|.:.||         :.:|:|          .:....|..
 Frog   770 AINVIQESLTIEVLCVGKMTPPRLRYSFYIPREKKDGKVGQVISNSLAGLPPPLPRLKPQSNWIA 834

  Fly   345 HQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACGTEPCAPHWVEGEWSKCS 409
            ..:..||.|||.|.|.|.:.|.:.   .|...|.|....:|.|.:.|| :|| |.|..||||.||
 Frog   835 GNWGDCSVSCGTGHQIRTIECRDP---WEQLASDCQAALRPSERRTCG-DPC-PVWDAGEWSSCS 894

  Fly   410 KGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNC 462
            |.||. ||:.|.:.|   |:.|..|:..:...||   .||.....||  ::.|
 Frog   895 KSCGR-GFKRRQLRC---SADGGVTLPREHCHLK---RKPQELDFCN--IRPC 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	21/51 (41%)
		ADAMTS_CR_3	116..213	CDD:437068	42/108 (39%)
		ADAMTS_spacer1	222..329	CDD:461796	33/114 (29%)
		TSP1_ADAMTS	347..396	CDD:465950	16/48 (33%)
		TSP1_ADAMTS	400..457	CDD:465950	22/56 (39%)
		TSP1_ADAMTS	465..520	CDD:465950
		TSP1_ADAMTS	580..632	CDD:465950
		TSP1_ADAMTS	643..693	CDD:465950
		MSCRAMM_ClfA	<1049..1262	CDD:468110
		Kunitz_papilin_lacunin-like	1612..1663	CDD:438681
		Kunitz_BPTI	1670..1721	CDD:425421
		Kunitz-type	1730..1780	CDD:438633
		Kunitz_BPTI	1789..1840	CDD:425421
		Kunitz_papilin_mig6-like	1849..1899	CDD:438679
		Kunitz_papilin_mig6-like	1922..1972	CDD:438679
		Kunitz_papilin_mig6-like	2001..2051	CDD:438679
		Kunitz-type	2071..2121	CDD:438633
		Kunitz_BPTI	2127..2178	CDD:425421
		Kunitz_BPTI	2193..2245	CDD:425421
		Kunitz_BPTI	2252..2303	CDD:425421
		Kunitz_BPTI	2317..2372	CDD:425421
		WAP	2455..2497	CDD:459672
		Ig	2530..2610	CDD:472250
		Ig strand B	2539..2543	CDD:409353
		Ig strand C	2552..2556	CDD:409353
		Ig strand E	2576..2579	CDD:409353
		Ig strand F	2589..2594	CDD:409353
		Ig strand G	2603..2606	CDD:409353
		IG_like	2627..2703	CDD:214653
		Ig strand B	2636..2640	CDD:409353
		Ig strand C	2649..2653	CDD:409353
		Ig strand E	2670..2674	CDD:409353
		Ig strand F	2684..2689	CDD:409353
		Ig strand G	2697..2700	CDD:409353
		I-set	2766..2845	CDD:400151
		Ig strand B	2771..2775	CDD:409353
		Ig strand C	2784..2788	CDD:409353
		Ig strand F	2821..2826	CDD:409353
		PLAC	2851..2883	CDD:462560
adamts15	XP_012822382.1	Pep_M12B_propep	30..158	CDD:460254
		ZnMc_ADAMTS_like	219..425	CDD:239801
		ADAMTS_CR_2	439..506	CDD:465496
		TSP1	520..572	CDD:214559	21/51 (41%)
		ADAMTS_CR_3	<615..681	CDD:437068	32/65 (49%)
		ADAMTS_spacer1	683..800	CDD:461796	34/121 (28%)
		TSP1_ADAMTS	832..882	CDD:465950	17/53 (32%)
		TSP1_ADAMTS	885..938	CDD:465950	23/61 (38%)