DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppn and adamts15

DIOPT Version :9

Sequence 1:NP_788752.2 Gene:Ppn / 43872 FlyBaseID:FBgn0003137 Length:2898 Species:Drosophila melanogaster
Sequence 2:XP_012822382.1 Gene:adamts15 / 100489270 XenbaseID:XB-GENE-6051208 Length:938 Species:Xenopus tropicalis


Alignment Length:443 Identity:150/443 - (33%)
Similarity:203/443 - (45%) Gaps:64/443 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 WTPWSSPSDCSRTCGGGVSYQTRECLRRD-DRGEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCS 123
            |..||....|||||||||....|||...: ..|.:.|.|...:|.||:...|||....||.:|| 
 Frog   520 WGKWSPYGQCSRTCGGGVQLAKRECNNPEPSNGGSFCEGLRVKYRSCSLNPCPETGKSFREEQC- 583

  Fly   124 RFDRQQFDGVFYE---------WVPYTNAPNP---CELNCMPKGERFYYRQREKVVDGTRCNDKD 176
                :.|:|..:.         |||..:..:|   |:|.|...|..::|....||||||.|:...
 Frog   584 ----ESFNGFNHSTNRITQTVGWVPKYSGVSPRDKCKLICRANGTGYFYVLSPKVVDGTPCSPDA 644

  Fly   177 LDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATN 241
            ..|||.|:|:..|||..|||..|.||||.||||..:||.| :.:.||.: .|||.::.:|.||:|
 Frog   645 TSVCVQGKCIKAGCDGQLGSKKKYDKCRVCGGDNKSCKKI-SGLFTKPI-HGYNFVVTIPAGASN 707

  Fly   242 IRIEE-----TVPSSNYLACRNHSGHYYLNGDWRIDF-PRPMFFANSWWNYQRKPMGFAAPDQLT 300
            :.:.:     .:...||||.:|..|.|.|||::.:.. .|.:....|...|....   .|.:.|.
 Frog   708 LDVRQRGYKGLINDDNYLAVKNAQGRYLLNGNYIVAAGERDISVRGSLLKYSGTG---TAVETLQ 769

  Fly   301 CSGPISESLFIVMLVQEKNI--SLDYEYSIP---------ESLSHS----------QQDTHTWTH 344
            ....|.|||.|.:|...|..  .|.|.:.||         :.:|:|          .:....|..
 Frog   770 AINVIQESLTIEVLCVGKMTPPRLRYSFYIPREKKDGKVGQVISNSLAGLPPPLPRLKPQSNWIA 834

  Fly   345 HQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACGTEPCAPHWVEGEWSKCS 409
            ..:..||.|||.|.|.|.:.|.:.   .|...|.|....:|.|.:.|| :|| |.|..||||.||
 Frog   835 GNWGDCSVSCGTGHQIRTIECRDP---WEQLASDCQAALRPSERRTCG-DPC-PVWDAGEWSSCS 894

  Fly   410 KGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNC 462
            |.||. ||:.|.:.|   |:.|..|:..:...||   .||.....||  ::.|
 Frog   895 KSCGR-GFKRRQLRC---SADGGVTLPREHCHLK---RKPQELDFCN--IRPC 938

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpnNP_788752.2 TSP1 60..111 CDD:214559 21/51 (41%)
ADAM_spacer1 214..329 CDD:283607 35/122 (29%)
TSP1 468..521 CDD:214559
TSP_1 645..693 CDD:278517
Kunitz_BPTI 1611..1663 CDD:278443
Kunitz_BPTI 1670..1721 CDD:278443
Kunitz_BPTI 1729..1781 CDD:278443
Kunitz_BPTI 1789..1840 CDD:278443
Kunitz_BPTI 1848..1899 CDD:278443
KU 1920..1973 CDD:238057
Kunitz_BPTI 2001..2051 CDD:278443
KU 2071..2121 CDD:238057
Kunitz_BPTI 2127..2178 CDD:278443
KU 2192..2245 CDD:238057
KU 2251..2304 CDD:238057
KU 2316..2372 CDD:238057
WAP 2457..2497 CDD:278522
Ig 2521..2610 CDD:299845
IG_like 2530..2610 CDD:214653
IG_like 2627..2703 CDD:214653
Ig 2636..2701 CDD:143165
IG_like 2766..2841 CDD:214653
Ig 2768..2830 CDD:299845
PLAC 2851..2883 CDD:285849
adamts15XP_012822382.1 Pep_M12B_propep 30..158 CDD:366707
ZnMc_ADAMTS_like 219..425 CDD:239801
ADAM_CR_2 439..506 CDD:375321
TSP1 520..572 CDD:214559 21/51 (41%)
ADAM_spacer1 682..800 CDD:368694 35/122 (29%)
TSP1 835..883 CDD:214559 18/52 (35%)
TSP1 884..938 CDD:214559 23/62 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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