Protein Alignment Ppn and adamts9

DIOPT Version :9

• Sequence 1: NP_788752.2
• Gene: Ppn / 43872
• FlyBaseID: FBgn0003137
• Length: 2898
• Species: Drosophila melanogaster
• Sequence 2: NP_001244125.1
• Gene: adamts9 / 100333407
• ZFINID: ZDB-GENE-070814-6
• Length: 1643
• Species: Danio rerio
• Alignment Length: 891
• Identity: 231/891 - (25%)
• Similarity: 339/891 - (38%)
• Gaps: 275/891 - (30%)

  Fly    60 WTPWSSPSDCSRTCGGGVSYQTRECLRRDDR-GEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCS 123
            |..||....||||||||:....|||.|...| |...|.|...::.|||::.|.:::.|||.:||:
Zfish   730 WGVWSPFGTCSRTCGGGIKIAVRECNRPVPRNGGKYCVGRRMKFRSCNSEPCSKQKKDFREEQCA 794

  Fly   124 RFDRQQF--DGV--FYEWVP-YTN--APNPCELNCMPKGERFYYRQREKVVDGTRCNDKDLDVCV 181
            .||.:.|  :|:  ...||| |:.  ..:.|:|.|...|...||:.|::|.|||:|.....|:||
Zfish   795 SFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVTDGTQCGPDTNDICV 859

  Fly   182 NGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATNIRIEE 246
            .|.|...|||.:|.|.|:.|||..||||.|:||.:..|...  :..|||.::.:|.|||||.:.:
Zfish   860 QGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKPVAGTFNI--VHYGYNVVVRIPSGATNIDVRQ 922

  Fly   247 -----TVPSSNYLACRNHSGHYYLNGDWRID-FPRPMFFANSWWNYQRKPMGFAAPDQLTCSGPI 305
                 .....||||..|..|.|.||||:.:. |.|.:...|:...|....   ...:::.|:..|
Zfish   923 HSYSGKAEDDNYLALSNSRGEYLLNGDFVVSMFKREVRVGNAVIEYSGSD---HVVERINCTDRI 984

  Fly   306 SESLFIVMLVQEK--NISLDYEYSIP--------------------------------------- 329
            .|.:.|.:|....  |..:.|.|:||
Zfish   985 EEEIIIQVLSVGNLYNPDVRYSYNIPIEDKPQHFFWDAYGPWQDCSLLCQGERKKKILCNRESDR 1049

  Fly   330 ----------------------------------------------------------------- 329
                                                                             
Zfish  1050 VVVSDQRCHGLPKPAAITESCNTDCELGWHIARKSECTAACGVGYRSLDIYCTKQSRLDGKTQKV 1114

  Fly   330 -------------ESLSHSQQDTHTWTHHQFNACSASCGGGSQSRKVTC--------------NN 367
                         :.:.|...:...|.:..::.||.|||||::.|...|              ..
Zfish  1115 DERYCSSQHKPNDKEVCHGDCNPGGWEYSSWSECSRSCGGGTRRRNAICGKSDERDDDSKCNPQE 1179

  Fly   368 RITLAEVNPSLCDQ-------------------------------------KSKPVEEQACGTEP 395
            ::|....|..||.|                                     .|||...|||..:.
Zfish  1180 KLTAQPCNEFLCPQWKTGDWSECLVTCGKGYKHRQTWCQFGEERLDVRFCDSSKPESVQACQQQE 1244

  Fly   396 CAPHWVEGEWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVK 460
            || .|..|.|.:|:..|| .|:|.|::.|. :.|.|  :|.:|..|  ....:|...|:|.  :.
Zfish  1245 CA-SWQVGPWGQCTTTCG-PGYQMRAVKCV-VGSYG--SVMDDTEC--NAATRPTDTQDCG--LS 1300

  Fly   461 NCPKYH-------------------LGPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVE 506
            .||..|                   .|.||.|...||.|.:.|.|:|..::.|   |..|..|..
Zfish  1301 QCPVTHPVAPEPKVMPHPGHKTQWRFGSWTQCSATCGKGTRMRYVSCRDQQGG---VAEESACAH 1362

  Fly   507 -EKPETEKSCLLTPCEGVDWIISQWSGCN-ACGQNTETRTAICGNKEGKVYPEEFCE-PEVPTLS 568
             .||...:.|.:..|.  .|.:.:|:.|: :|||.|.||..:|.|...:|.....|: .:.|...
Zfish  1363 LPKPPASEVCSIVACG--QWKVLEWTACSVSCGQGTTTRQVVCMNISDQVVELSECDLDDKPAAE 1425

  Fly   569 RPCKSPKCEA-----------------------------------QWFSSEWSKCSAPCGKGVKS 598
            :.|..|:|.:                                   ||.:..|..||:.|..|.:.
Zfish  1426 QECAMPQCPSRSSDHGGFSPNPDFRKKTALPGRTDRNRAGRLQAQQWRTGPWGACSSTCAGGFQR 1490

  Fly   599 RIVICGEFDGKTVTPADDDSKCNKETKPESEQDCEGEEKVCPGEWFTGPWGKCSKPCGGGERVRE 663
            |:|:|.:.:|   .||   |.|::..:|..::.||...  || :||.|.|.:|||.||||.:.|.
Zfish  1491 RVVVCQDENG---YPA---SSCDESIQPIEQRSCESGS--CP-QWFYGSWSECSKSCGGGIKTRL 1546

  Fly   664 VLC-LSNGTK--SVNCDEEKVEPLSEKCNSEACTEDEILPLTSTDK 706
            |.| ..||.:  .::|:.....|..|:||:::|:   |.|..|||:
Zfish  1547 VACQRPNGERFNDLSCEILDKPPDREQCNTQSCS---INPHWSTDQ 1589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppn	NP_788752.2	TSP1	60..111	CDD:214559	22/51 (43%)
		ADAM_spacer1	214..329	CDD:283607	34/122 (28%)
		TSP1	468..521	CDD:214559	17/53 (32%)
		TSP_1	645..693	CDD:278517	19/50 (38%)
		Kunitz_BPTI	1611..1663	CDD:278443
		Kunitz_BPTI	1670..1721	CDD:278443
		Kunitz_BPTI	1729..1781	CDD:278443
		Kunitz_BPTI	1789..1840	CDD:278443
		Kunitz_BPTI	1848..1899	CDD:278443
		KU	1920..1973	CDD:238057
		Kunitz_BPTI	2001..2051	CDD:278443
		KU	2071..2121	CDD:238057
		Kunitz_BPTI	2127..2178	CDD:278443
		KU	2192..2245	CDD:238057
		KU	2251..2304	CDD:238057
		KU	2316..2372	CDD:238057
		WAP	2457..2497	CDD:278522
		Ig	2521..2610	CDD:299845
		IG_like	2530..2610	CDD:214653
		IG_like	2627..2703	CDD:214653
		Ig	2636..2701	CDD:143165
		IG_like	2766..2841	CDD:214653
		Ig	2768..2830	CDD:299845
		PLAC	2851..2883	CDD:285849
adamts9	NP_001244125.1	Pep_M12B_propep	35..165	CDD:279848
		Pep_M12B_propep	217..347	CDD:279848
		Reprolysin	429..638	CDD:279729
		ZnMc_ADAMTS_like	429..635	CDD:239801
		TSP1	730..782	CDD:214559	22/51 (43%)
		ADAM_spacer1	892..1010	CDD:283607	34/122 (28%)
		TSP1	1140..1192	CDD:214559	13/51 (25%)
		TSP1	1194..1245	CDD:214559	6/50 (12%)
		TSP1	1248..1303	CDD:214559	18/62 (29%)
		TSP1	1324..>1352	CDD:214559	10/27 (37%)
		TSP1	1377..1434	CDD:214559	17/58 (29%)
		TSP1	1472..1524	CDD:214559	17/59 (29%)
		TSP1	1526..1580	CDD:214559	21/53 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910