DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amx and TM2D3

DIOPT Version :9

Sequence 1:	NP_001245591.1	Gene:	amx / 43869	FlyBaseID:	FBgn0000077	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_510883.2	Gene:	TM2D3 / 80213	HGNCID:	24128	Length:	247	Species:	Homo sapiens

Alignment Length:	185	Identity:	95/185 - (51%)
Similarity:	119/185 - (64%)	Gaps:	11/185 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 PYDKETP----CDRLQFPCIRCNYNHGCIYGRDLNVTCEVINNVQCL-----GERSFQRQMNCRY 166
            ||..:.|    |.||...||.|..|..|.||:.:...|.|..:|.|:     .:::|...|.||:
Human    63 PYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRF 127

  Fly   167 CYQTEMWQQSCGQRSSCN--SATDKLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLI 229
            |:|.......|...:||.  |...:.:..||||...|.|||||:|.:.|.||||.||:|||||.:
Human   128 CWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALAL 192

  Fly   230 SLTLGGFGADRFYLGHWQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI 284
            |:|||||||||||||.|:||:||||||||||:||:||||||.:.|:|||||||||
Human   193 SITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amx	NP_001245591.1	TM2	219..268	CDD:282945	38/48 (79%)
TM2D3	NP_510883.2	TM2	182..231	CDD:282945	38/48 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152765
Domainoid	1	1.000	92	1.000	Domainoid score	I7621
eggNOG	1	0.900	-	-		E1_KOG4272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12275
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3817
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385397at2759
OrthoFinder	1	1.000	-	-		FOG0005547
OrthoInspector	1	1.000	-	-		oto90265
orthoMCL	1	0.900	-	-		OOG6_106920
Panther	1	1.100	-	-	LDO	PTHR21016
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.760