DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amx and tm2d3

DIOPT Version :9

Sequence 1:	NP_001245591.1	Gene:	amx / 43869	FlyBaseID:	FBgn0000077	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_002937906.1	Gene:	tm2d3 / 100145816	XenbaseID:	XB-GENE-5805754	Length:	247	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	104/234 - (44%)
Similarity:	135/234 - (57%)	Gaps:	24/234 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 VSSMVAKSGGG----------AGGLLDNITAYSSSSSSSSSNGNNNMLCPYDKETP----CDRLQ 122
            ::.|...||.|          |..|.|:   :.||:.::|:......:..|.::.|    |.||.
Frog    17 ITQMYVLSGRGFLSFEYSEPVAQPLKDH---FPSSTIATSTRATATKIPDYMEKCPSNGQCSRLP 78

  Fly   123 FPCIRCNYNHGCIYGRDLNVTCEVINNVQCLGERS-----FQRQMNCRYCYQTEMWQQSCGQRSS 182
            ..|:.|..|:.||||:.:...|...|.|.|....|     |...|.|::|:|.......|...||
Frog    79 SDCMTCATNYSCIYGKPVTFNCTAKNGVVCFDVNSQPQEYFTISMTCQFCWQLPPSDYVCNLSSS 143

  Fly   183 CN--SATDKLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLISLTLGGFGADRFYLGH 245
            |.  |...:.:.|.|||.....|||||:|.:.|.||||.||:|||||.:|:|||||||||||||.
Frog   144 CKTVSCPRQRYNTTCTVLDHAHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQ 208

  Fly   246 WQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI 284
            |:||:||||||||||:||:|||.|||:.|:|||||||||
Frog   209 WREGLGKLFSFGGLGIWTLIDVFLISVGYVGPADGSLYI 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amx	NP_001245591.1	TM2	219..268	CDD:282945	38/48 (79%)
tm2d3	XP_002937906.1	TM2	182..231	CDD:377473	38/48 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7484
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12275
Inparanoid	1	1.050	197	1.000	Inparanoid score	I3689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385397at2759
OrthoFinder	1	1.000	-	-		FOG0005547
OrthoInspector	1	1.000	-	-		otm48697
Panther	1	1.100	-	-	LDO	PTHR21016
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2847
SonicParanoid	1	1.000	-	-		X3965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100