DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf3 and atf7b

DIOPT Version :9

Sequence 1:	NP_001259125.1	Gene:	Atf3 / 43867	FlyBaseID:	FBgn0028550	Length:	688	Species:	Drosophila melanogaster
Sequence 2:	XP_005166106.1	Gene:	atf7b / 567018	ZFINID:	ZDB-GENE-030131-3028	Length:	459	Species:	Danio rerio

Alignment Length:	375	Identity:	92/375 - (24%)
Similarity:	147/375 - (39%)	Gaps:	76/375 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LSIDSGGLLMGGHTPKTPEILNSLIAMTNPLENFSYSSAAAAAAAVSVASSS---ASCSAASTPV 73
            |.|||.       .|.:|:   |..:|||     |..:.|.|..|:::..:.   ...:|:|||.
Zfish   109 LEIDSS-------PPDSPD---SASSMTN-----SKDTVAMAKEAIALRKAKDVPPRTAASSTPT 158

  Fly    74 VTVRHFNGHP-----NGQSHSQDSSHSSCSGSP----LDSPAGTATTPSVQ-----QTCSRLIKE 124
            .|:......|     :..:.:|.|..|..:.:|    |.||:|  :.|.:.     ||...|...
Zfish   159 PTIVRPGSLPLHQGFDSMNPTQPSPTSVITRTPPSNRLSSPSG--SFPMLMQLPNGQTVPLLPSP 221

  Fly   125 GLKLSIQSKRKLSTC------------DSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNAN 177
            |....|...|..:|.            .|||||..|        |.::.||.:......::|..:
Zfish   222 GQTSVISLARSSNTVPNIPGIPGPPIGGSSSGSSSP--------SGYSTHSDAKTRLKAALSQPS 278

  Fly   178 DLDDDCEESSDDDSETKS--QP-------------KGLTPEDEDRRRRRRERNKIAATKCRMKKR 227
            . .........|.:||.|  ||             :|...|.::||||..|||:.||::||.|::
Zfish   279 P-SGPAPIQKTDHTETPSPAQPQVSPAPPKGGRRRRGADIEPDERRRRFLERNRAAASRCRQKRK 342

  Fly   228 ERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLS 292
            .....|.|.:|.|...||.|..:|..|.||..:|.::|.:|........|..:.|.....:..:|
Zfish   343 VWVSALEKRAEELANANVSLTGEVSLLRTEVTRLKELLLAHKDCPVTAMQKKAYLAAGVDESSVS 407

  Fly   293 ELELETVSIDGPNSGNN-----NQRLQSIPSMATFKYGSKTAAAMAQQLP 337
            .|.: .|::..|.|.|.     .:.:..:..|.:.::.:....|.:|..|
Zfish   408 ALVM-PVTVPAPVSVNGLSVRAAEAVAVLAGMGSGQWSNSAGDASSQSQP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	19/52 (37%)
Atf3	NP_001259125.1	coiled coil	215..265	CDD:269870	18/49 (37%)
atf7b	XP_005166106.1	C2H2 Zn finger	9..31	CDD:275368
		bZIP_ATF2	332..382	CDD:269835	18/49 (37%)
		coiled coil	332..382	CDD:269835	18/49 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900