DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf3 and fosl1a

DIOPT Version :9

Sequence 1:	NP_001259125.1	Gene:	Atf3 / 43867	FlyBaseID:	FBgn0028550	Length:	688	Species:	Drosophila melanogaster
Sequence 2:	XP_009289400.1	Gene:	fosl1a / 564241	ZFINID:	ZDB-GENE-061207-7	Length:	347	Species:	Danio rerio

Alignment Length:	390	Identity:	99/390 - (25%)
Similarity:	150/390 - (38%)	Gaps:	87/390 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GHP-NGQSHSQDSSHSSCSGSPLDSPAGTATTPSVQQTCSRLIKEGLKL----SIQSKRKLS-TC 139
            |:| .|...|...|.|..|||...|.|.|..|...||....:...|..:    :|.|.:.|. ..
Zfish     5 GNPGRGIDRSFPESSSGSSGSSSASVATTTGTTQQQQQKYSVAGSGQFVPSLNAITSNQSLQWML 69

  Fly   140 DSSSGSEQP----HSKY------------SRRSSNHNGHSGSSNNYS--GSMSNANDLDDDCEES 186
            ..|.|:..|    .|.|            .:.|.:|....|.....:  ||.:..||
Zfish    70 QPSIGTPGPSRALRSSYPLPPGIPATMNPPQPSQSHLSRPGVIRAAAAIGSTTRRND-------- 126

  Fly   187 SDDDSETKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQV 251
                       :.|:||:.:|||.||||||:||.|||.::||.|..|..|::.|:.:...|:.::
Zfish   127 -----------EYLSPEELERRRIRRERNKMAAAKCRNRRRELTDTLQNETDQLEDEKSRLQKEI 180

  Fly   252 RQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQK---YLSELELETVSIDGPNSGNNNQRL 313
            ..|:.|::||..:.::|    ...|::......|.:..   .||.:::|.|..|.|.
Zfish   181 ADLQKEKEKLELVFEAH----RPICKVQESESDSDSSNDIPSLSGIKIEPVDPDLPG-------- 233

  Fly   314 QSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQQQQQQ---QPQSLNPAGN 375
               ||..|..|     |.:.:..|.....|.|||...  .|...:.:.....   ...||.|...
Zfish   234 ---PSRETKHY-----AKINKPKPKITIPPPPSASSI--TGIPLESESLHTPVLISTPSLTPFTA 288

  Fly   376 NVIDQQHANPSPSL-LSDYVPNCDGLTGSASNHPSHNN------NNNNNNSSGASSNTSNNNSNI 433
            :::   .:.||.|| .|....|.      .::|||..|      .:..::|||..|:.|.|:..|
Zfish   289 SLV---FSYPSTSLDTSSQALNL------VTSHPSSQNPQPCAVAHRRSSSSGDQSDHSLNSPTI 344

Fly 434 433
Zfish 345 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	18/52 (35%)
Atf3	NP_001259125.1	coiled coil	215..265	CDD:269870	18/49 (37%)
fosl1a	XP_009289400.1	bZIP_Fos	144..197	CDD:269869	18/52 (35%)
fosl1a	XP_009289400.1	coiled coil	144..196	CDD:269869	18/51 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576076
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740