DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf3 and BATF2

DIOPT Version :9

Sequence 1:	NP_001259125.1	Gene:	Atf3 / 43867	FlyBaseID:	FBgn0028550	Length:	688	Species:	Drosophila melanogaster
Sequence 2:	NP_612465.3	Gene:	BATF2 / 116071	HGNCID:	25163	Length:	274	Species:	Homo sapiens

Alignment Length:	248	Identity:	59/248 - (23%)
Similarity:	99/248 - (39%)	Gaps:	62/248 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 TKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETE 257
            |::.||      |.:|:.::::|:.||.:.|.|..::...|.::.|.|:..|:.|:.:::.|:.|
Human    11 TQTDPK------EQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALRKEIQSLQAE 69

  Fly   258 ----------RQKLVDM-------------------LKSHGCQRAGGCQLPSQLLQSPAQKYLSE 293
                      .::|..|                   |...|.|...||:...:|.|:|...|
Human    70 LAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQLELFQTPGSCY--- 131

  Fly   294 LELETVSIDGPNSGNNNQRLQ-SIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEF-EHAGYQ 356
             ..:.:| .||...::...|| .:||::   .|....|....||       |||...| .|.|
Human   132 -PAQPLS-PGPQPHDSPSLLQCPLPSLS---LGPAVVAEPPVQL-------SPSPLLFASHTG-- 182

  Fly   357 QQQQQQQQQQPQSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGSASNHPS 409
             ...|....:..:|.|:    :..|.|.|.|..|..  |. .|..||:.::||
Human   183 -SSLQGSSSKLSALQPS----LTAQTAPPQPLELEH--PT-RGKLGSSPDNPS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf3	NP_001259125.1	bZIP_ATF3	215..268	CDD:269870	15/81 (19%)
Atf3	NP_001259125.1	coiled coil	215..265	CDD:269870	14/78 (18%)
BATF2	NP_612465.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..47		11/41 (27%)
		bZIP_BATF	17..74	CDD:269849	14/56 (25%)
		coiled coil	19..73	CDD:269849	13/53 (25%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	20..41		6/20 (30%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	45..66		5/20 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..151		5/27 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..229		13/48 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840