DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HnRNP-K and AT1G51580

DIOPT Version :9

Sequence 1:	NP_995906.1	Gene:	HnRNP-K / 43862	FlyBaseID:	FBgn0267791	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_175569.1	Gene:	AT1G51580 / 841583	AraportID:	AT1G51580	Length:	621	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	100/507 - (19%)
Similarity:	162/507 - (31%)	Gaps:	186/507 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EGEGPQDQKRNR---RNEETVRILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDD--SQGPERT 73
            |..||    .||   ..|...|:|.|:...|::|||||..::.::.:..|::.|.|  ....||.
plant   262 EDVGP----FNRPVVEEEVAFRLLCPADKVGSLIGKGGAVVRALQNESGASIKVSDPTHDSEERI 322

  Fly    74 IQISA--DIE--------STLEIITEMLKYFEERDEDFDVRLLIHQSLAGCVIGKGGQKIKEIRD 128
            |.|||  ::|        ..:.:...:::...|.......|||:|....|.::||||..|.|:|.
plant   323 IVISARENLERRHSLAQDGVMRVHNRIVEIGFEPSAAVVARLLVHSPYIGRLLGKGGHLISEMRR 387

  Fly   129 RIGCRFLKVFSNVAPQST------DRVVQTVGKQSQVIEAVREVITLTRDTPIKGAIHNYDPMNF 187
            ..|.. ::||:.  .|:|      |.:||.:|....|.:|:.:::...|:....|.:
plant   388 ATGAS-IRVFAK--DQATKYESQHDEIVQVIGNLKTVQDALFQILCRLREAMFPGRL-------- 441

  Fly   188 DRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGGFNAGGARGNAGGRGGADRF 252
                               |.|
plant   442 -------------------PFQ------------------------------------------- 444

  Fly   253 GGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNAGGAGGFAGNSFGGGAGGPFGGGSFGN 317
                       |||....||:.|:                                |.....||.
plant   445 -----------GMGGPPPPFMGPY--------------------------------PEPPPPFGP 466

  Fly   318 NGFGGGPSDFGGNSGNFGQ----AQGTNSLPSLGSFSQNQGGTSSLPSLGSFGQNPGG--PGGLG 376
            ..:...|..:....|.|.:    ..|.:..|..| |.:.....|..|..|..| :|||  |..:.
plant   467 RQYPASPDRYHSPVGPFHERHCHGPGFDRPPGPG-FDRPPSPMSWTPQPGIDG-HPGGMVPPDVN 529

  Fly   377 NGLSGGANGGVGTLGGANGAGGFNAVGGANGGPNGSPN---AATNVPQGHDPNNSTQVTIPKELA 438
            :|.:                        ....|.||.|   .:.||          ::.||:...
plant   530 HGFA------------------------LRNEPIGSENPVMTSANV----------EIVIPQAYL 560

  Fly   439 GAIIGKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQYLL 490
            |.:.|:....:..|:..|.|.:.:.:|...:.:.::.:|||..|...||.||
plant   561 GHVYGENCSNLNYIKQVSGANVVVHDPKAGTTEGLVVVSGTSDQAHFAQSLL 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HnRNP-K	NP_995906.1	PCBP_like_KH	30..91	CDD:239089	19/72 (26%)
HnRNP-K	NP_995906.1	PCBP_like_KH	103..167	CDD:239089	23/69 (33%)
AT1G51580	NP_175569.1	KH-I	21..83	CDD:412160
		KH-I_PEPPER_rpt2_like	149..221	CDD:411888
		KH-I_PEPPER_rpt1_like	275..343	CDD:411887	20/67 (30%)
		KH-I	361..433	CDD:412160	23/74 (31%)
		KH-I	551..616	CDD:412160	17/72 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I4773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2078
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1137
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X348
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060