Protein Alignment HnRNP-K and Hnrnpk

DIOPT Version :9

• Sequence 1: NP_995906.1
• Gene: HnRNP-K / 43862
• FlyBaseID: FBgn0267791
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_006253615.1
• Gene: Hnrnpk / 117282
• RGDID: 71058
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 187/528 - (35%)
• Similarity: 239/528 - (45%)
• Gaps: 129/528 - (24%)

  Fly     6 RMKREMNDEGEGPQDQKRNRRNEETV--RILIPSSIAGAVIGKGGQHIQKMRTQYKATVSVDDSQ 68
            |...:|.:|    |..||:|..:|.|  |||:.|..|||||||||::|:.:||.|.|:|||.||.
  Rat    22 RPAEDMEEE----QAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS 82

  Fly    69 GPERTIQISADIESTLEII----------------------------TEMLKYFEERDEDFD--V 103
            ||||.:.||||||:..||:                            .|.|.|...:..|||  :
  Rat    83 GPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCEL 147

  Fly   104 RLLIHQSLAGCVIGKGGQKIKEIRDRIGCRFLKVFSNVAPQSTDRVVQTVGKQSQVIEAVREVIT 168
            ||||||||||.:||..|.||||:|:..... :|:|....|.||||||...||..:|:|.::.::.
  Rat   148 RLLIHQSLAGGIIGVKGAKIKELRENTQTT-IKLFQECCPHSTDRVVLIGGKPDRVVECIKIILD 211

  Fly   169 LTRDTPIKGAIHNYDPMNFDRVYADEYGGYGTGSGSTRPSQRGNNRNGGGAGGVAGGAAGGNGGG 233
            |..::||||....|||..:|..|  :|||:         :...::|.|...|
  Rat   212 LISESPIKGRAQPYDPNFYDETY--DYGGF---------TMMFDDRRGRPVG------------- 252

  Fly   234 FNAGGARGNAGGRGGADRFGGAAGGAVAGAGMGQRDNPFINPWANGGGGDVDGFGNNAGGAGGFA 298
                   ....||||.||.....||.....  .:||...::| ..|......|    .||.||..
  Rat   253 -------FPMRGRGGFDRMPPGRGGRPMPP--SRRDYDDMSP-RRGPPPPPPG----RGGRGGSR 303

  Fly   299 GNSFGGGAGGPFGGGSFGNNGFGGGPSD-FGGNSGNFGQAQGTNSLPSLGSFSQNQGGTSSL--- 359
            ..:.......|..||........|.|.| :.|..|                ||.::...|::
  Rat   304 ARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG----------------FSADETWDSAIDTW 352

  Fly   360 -PSLGSFGQNPGGPGGLGNGLSGGANGGVGTLGGANGAGGFNAVGGANGGPNGSPNAATNVPQGH 423
             ||.......|.|..|.....:|| .|..|.|||
  Rat   353 SPSEWQMAYEPQGGSGYDYSYAGG-RGSYGDLGG------------------------------- 385

  Fly   424 DPNNSTQVTIPKELAGAIIGKGGGRIRRIRNESSAYITIDEPLPNSNDRIITISGTPKQIQMAQY 488
             |..:|||||||:|||:||||||.||::||:||.|.|.|||||..|.||||||:||..|||.|||
  Rat   386 -PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQY 449

  Fly   489 LLQQSVHE 496
            |||.||.:
  Rat   450 LLQNSVKQ 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HnRNP-K	NP_995906.1	PCBP_like_KH	30..91	CDD:239089	37/90 (41%)
		PCBP_like_KH	103..167	CDD:239089	31/63 (49%)
Hnrnpk	XP_006253615.1	ROKNT	4..43	CDD:400419	8/24 (33%)
		KH-I_HNRNPK_rpt1	42..105	CDD:411860	36/62 (58%)
		KH-I_HNRNPK_rpt2	144..213	CDD:411861	32/69 (46%)
		KH-I_HNRNPK_rpt3	387..460	CDD:411862	49/71 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340899
Domainoid	1	1.000	91	1.000	Domainoid score	I7527
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3473
OMA	1	1.010	-	-		QHG48676
OrthoDB	1	1.010	-	-		D394765at2759
OrthoFinder	1	1.000	-	-		FOG0005459
OrthoInspector	1	1.000	-	-		oto96602
orthoMCL	1	0.900	-	-		OOG6_105766
Panther	1	1.100	-	-	LDO	PTHR10288
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X348
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910