DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and GCN5

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_011768.1	Gene:	GCN5 / 853167	SGDID:	S000003484	Length:	439	Species:	Saccharomyces cerevisiae

Alignment Length:	150	Identity:	38/150 - (25%)
Similarity:	70/150 - (46%)	Gaps:	19/150 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1672 GAVDIKPKTETKPLVPEPLAPNAGDKKKKCQFNPEELRTALLP-----------TLEKLYRQEPE 1725
            |....|.....||:.|..: |..    |:..:.||....|..|           .|.:| :....
Yeast   290 GLEQFKDLNNIKPIDPMTI-PGL----KEAGWTPEMDALAQRPKRGPHDAAIQNILTEL-QNHAA 348

  Fly  1726 SVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTS 1790
            :.||..||:.:.  :|||::.:|:||||.|:...:::.||....:::.|..|:|:|..:||.:.:
Yeast   349 AWPFLQPVNKEE--VPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENT 411

  Fly  1791 RVYRYCTKLSEVFEAEIDPV 1810
            ..|:|..:|.:.|..::..:
Yeast   412 SYYKYANRLEKFFNNKVKEI 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927	31/116 (27%)
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
GCN5	NP_011768.1	COG5076	77..439	CDD:227408	38/149 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900