Protein Alignment nej and Brd8

DIOPT Version :9

• Sequence 1: NP_001188575.1
• Gene: nej / 43856
• FlyBaseID: FBgn0261617
• Length: 3282
• Species: Drosophila melanogaster
• Sequence 2: XP_008770251.2
• Gene: Brd8 / 291691
• RGDID: 1307003
• Length: 1206
• Species: Rattus norvegicus
• Alignment Length: 1198
• Identity: 234/1198 - (19%)
• Similarity: 362/1198 - (30%)
• Gaps: 452/1198 - (37%)

  Fly   927 VAGGAGGGNGGNTGPPGDNEKDW--RESVTADLRNHLVH-------KLVQAIFPTSDPTTMQD-- 980
            :|.|.|.....:|||    .:.|  ||.:.  |.:.::.       .:.:||.|.::|....|
  Rat     1 MATGTGKHKLLSTGP----TEPWSIREKLC--LASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWF 59

  Fly   981 KRMHNLVSYAEKVEKDMYEMAKSRSE------------YYHLLAEKIYKIQKELEE-----KRLK 1028
            .:.|....|:|.:|.......| |.|            ...|.||::.:::|.::|     :|||
  Rat    60 SQKHCASQYSELLETTETPKRK-RGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLK 123

  Fly  1029 RKEQHQQMLMQQQGVANPVAGGAAGGAGS-----AAGVAGGVVLPQQQQQQQQQQQQQGQQPLQS 1088
            |..:    |:|            ||...|     .:.:|....|.:::.:.:::......|..|:
  Rat   124 RDAE----LIQ------------AGHMDSRLDELCSDIAMKKKLEEEEAEVKRKATDAAYQARQA 172

  Fly  1089 CIHP--------------SISPMGGVMPPQQLRPQGPPGILGQQTAAGLGVGVGVTNNMVTMRSH 1139
            ...|              |.|| ||..|...|.|                         .||...
  Rat   173 VKTPPRRLPTVMVRSPIDSASP-GGDYPLGDLTP-------------------------TTMEEA 211

  Fly  1140 SPGGNMLALQQQQRMQFPQQQQQQPPGSGAGKMLVGPPGPSPGGMVVNPALSPYQTTNVLTSPVP 1204
            :.|.....|.......||......||||.                   |..:|       .:||.
  Rat   212 TSGVTPGTLPSTPVTSFPGIPDTLPPGSA-------------------PLEAP-------MTPVT 250

  Fly  1205 GQQQQQQFINANGGTGANPQLSEIMKQRHIHQQQQQQQQQQQQGMLLPQSPFSNSTPLQQQQQQQ 1269
            ....|::.:........:|.|||::|                :|.|||.||
  Rat   251 DDSPQKKMLGQKATPPPSPLLSELLK----------------KGSLLPTSP-------------- 285

  Fly  1270 QQQQQQQQATSNSFSSPMQQQQQGQQQQQQKPGSVL-----NNMPPTPTSLEALNAGAGAPGTGG 1329
                    ...|....|:............:.|.||     .::.|..:::.|..|.:|||....
  Rat   286 --------RLVNESEMPVPSGHLSSTGVLLEVGGVLPMIHGGDIQPATSAVAASPAASGAPTLSR 342

  Fly  1330 --SASNVTVSAPSPSPGFLSNGPSIGTPSNNNNNSSANNNPPSVSSLMQQPLSNRPGTPPYIPAS 1392
              .|.....|.|.||...:::.|.:...            ||.|.|:.|       .|...:||.
  Rat   343 LLEAGPTQFSTPLPSFTTVASEPPVKLV------------PPPVESVSQ-------ATIVMMPAL 388

  Fly  1393 PVPATSASGLAASSTPASAAATCASSGSGSNSSSGATAAGASSTSSSSSAGSGTPLSSVSTPTSA 1457
            |.|    |...|.|||.|.|..                         |......||.:|..|.:.
  Rat   389 PAP----SSAPAVSTPESVAPV-------------------------SQPEPCVPLEAVGDPQTV 424

  Fly  1458 TMATSSGGGGGGGGNAGGGSSTTPASNPL---LLMSG-GTAGGGTGATTTTSTS--SSSRMMSSS 1516
            |::..|             |..:...|.:   ...|| ..|.||:.|.:.....  ..:..|..:
  Rat   425 TVSMDS-------------SEISMIINSIKEECFRSGVAEAPGGSKAPSIDGKEDLDLAEKMDIA 476

  Fly  1517 SSLSSQ--------------------------MAALEAA---ARDNDD----------------- 1535
            .|.:.:                          :||:|||   ..:|||
  Rat   477 VSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERD 541

  Fly  1536 ---ETPSP---------------------------SG-----ENTNGSGGSGNAGGMASKGKLDS 1565
               ..|:|                           ||     |.|....|...|..:|..|.:.|
  Rat   542 KPVPLPAPEMTVKQERLDFEESETKGIHELVDIRDSGVEIKVEPTEPEPGMSGAEIVAGVGPVPS 606

  Fly  1566 IK----QDDDIKKEFMDDSCGGNNDSSQMDCSTGGGKGKNVNNDGTSMIKMEIK----------- 1615
            ::    :..|:.:|....:.|   :..:.|.|:|.|:.:.:     ..:|.|..
  Rat   607 LEPPELRSQDLDEEPRSSAAG---EMGEADGSSGKGEERPL-----PAVKTEASPESMLSPSHGS 663

  Fly  1616 --TEDGLDGEVKIKTEAMD--VDEAG---GS----TAGEHHGEGG--------------GGSGVG 1655
              .||.|:.|.:.|.|..|  .:|:|   ||    ..||...|.|              .|.|..
  Rat   664 NPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEEEEEDGVSEAASLEEPKEEDQGEGYL 728

  Fly  1656 GGKDN---INGAHDGGATGGAVDIKPKTETKPLVPEPLAPNAGDKKKKCQFNPEELRTALLPTLE 1717
            ...||   ::.:.||.:...|. ::..|....:...|    |..:...|..:.|.::.      :
  Rat   729 SEMDNEPPVSESDDGFSIHNAT-LQSHTLGDSIPSSP----ASSQFSVCSEDQEAIQA------Q 782

  Fly  1718 KLYRQEPESV-----------PFRYPVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEY 1771
            |::::....|           .|..||....  .|.|..||::||||.||:.||:||......|:
  Rat   783 KIWKKAIMLVWRAAANHRYANVFLQPVTDDI--APGYHSIVQRPMDLSTIKKNIENGLIRSTAEF 845

  Fly  1772 VDDVWLMFDNAWLYNRKTSRVYRYCTKLS-EVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQ 1835
            ..|:.|||.||.:||.....||....::. :|.|    .:.|.|
  Rat   846 QRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE----QIQQFL--------------------- 885

  Fly  1836 LCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQIKKDQFKEMKN 1900
                   |.....|.|  |.|:::....                |.|..:.|...:||.. .|.:
  Rat   886 -------ATQLIMQTS--ESGISAKSLR----------------GRDSTRKQDASEKDSV-PMGS 924

  Fly  1901 DHLELEPFVNCQECGRKQHQICVLWLDS 1928
            ....|..||.|:          .:||||
  Rat   925 PAFLLSLFVGCE----------WVWLDS 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354	20/100 (20%)
		Bromo_cbp_like	1705..1812	CDD:99927	33/118 (28%)
		RING_CBP-p300	1824..1906	CDD:276805	11/81 (14%)
		PHD_CBP_p300	1908..1939	CDD:277032	7/21 (33%)
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
Brd8	XP_008770251.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900