DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and Brd8dc

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_808441.2	Gene:	Brd8dc / 271508	MGIID:	3045347	Length:	273	Species:	Mus musculus

Alignment Length:	234	Identity:	54/234 - (23%)
Similarity:	96/234 - (41%)	Gaps:	24/234 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1577 MDDSCGGNNDSSQMDCSTGGGKGKNVNNDGTSMIKMEIKTEDGL-DGEVKIKTEAMDVDEAGGST 1640
            :|...|...|:...:......|..:.....:.::..::::|:.. :.|.....|.:...||...:
Mouse    39 LDLDVGSWKDTEDAEAEADEPKESSPERGCSELLVGDVESEEAREEAEQGTPQELLSEGEAQQDS 103

  Fly  1641 AGEHHGEGGGGSGVGGGKDNINGAHDGGATGGAVDIKPKTETKPLVPEPLAPNAGDKKKKCQFNP 1705
            ..:..|||....|           .|....|....|  :.:..|||  .:..::.......|.:|
Mouse   104 KEDDQGEGSASDG-----------EDTPPLGEGEGI--RVQEAPLV--NILYSSSQLNDLSQGDP 153

  Fly  1706 EELRTALLPTLEKLYRQEPE---SVPFRYPV-DPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYS 1766
            .:.:.....||.::::....   |.||..|| :.||   |.|.::||:||||.|::.|:..|:..
Mouse   154 IQDQFLFKKTLLQVWKMIASHRFSSPFLKPVSEKQA---PGYKDVVKRPMDLTTLKRNLSKGRIH 215

  Fly  1767 DPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLS-EVFE 1804
            ...|:..|:.|||.||.:||.....:|....::. ||.|
Mouse   216 TMAEFQRDLMLMFQNAVMYNDSDHHIYHMAVEMQREVLE 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927	34/105 (32%)
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
Brd8dc	NP_808441.2	Bromo_brd8_like	160..259	CDD:99939	33/98 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900