DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and Kat2b

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_064389.2	Gene:	Kat2b / 18519	MGIID:	1343094	Length:	813	Species:	Mus musculus

Alignment Length:	127	Identity:	36/127 - (28%)
Similarity:	65/127 - (51%)	Gaps:	3/127 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1681 ETKPLVPEPLAPNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFE 1745
            |:.|.:.|.....:|.:|.|...:||:|.:.|...|::: :..|.:.||..||  :....|.|:|
Mouse   682 ESIPGIRETGWKPSGKEKSKEPKDPEQLYSTLKNILQQV-KNHPNAWPFMEPV--KRTEAPGYYE 743

  Fly  1746 IVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEI 1807
            :::.||||.|:...::|..|.....::.|:..:|.|...||...|..|:..:.|.:.|.::|
Mouse   744 VIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASILEKFFFSKI 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927	30/103 (29%)
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
Kat2b	NP_064389.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		PCAF_N	56..307	CDD:283997
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	380..423
		COG5076	468..807	CDD:227408	36/127 (28%)
		Acetyltransf_1	531..603	CDD:278980
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q92830	555..557
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q92830	562..568
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q92830	593..596
		Bromo_gcn5_like	708..807	CDD:99941	28/101 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900