DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and C29F9.5

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_001355379.1	Gene:	C29F9.5 / 183022	WormBaseID:	WBGene00016220	Length:	261	Species:	Caenorhabditis elegans

Alignment Length:	103	Identity:	41/103 - (39%)
Similarity:	52/103 - (50%)	Gaps:	15/103 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 IQQQLMLLLHAHKCNRRE---------NLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHC 576
            |.:||.||||||:|.||:         |......:|.:..|..||.||.||.:||:...|...||
Worm    40 ISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKCNSVHC 104

  Fly   577 ASSRQILLHYKTCQNSGCVICYPFRQNHSVFQNANVPP 614
            ||||.||.|:|.|.|..|.:|.|      :.:....||
Worm   105 ASSRTILSHWKKCFNEECPVCKP------IIEQRTAPP 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717	32/78 (41%)
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
C29F9.5	NP_001355379.1	ZnF_TAZ	40..128	CDD:214717	39/93 (42%)
C29F9.5	NP_001355379.1	KIX	153..223	CDD:280354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166115
Domainoid	1	1.000	84	1.000	Domainoid score	I5261
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2676
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.690