DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and sepa-1

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_493339.1	Gene:	sepa-1 / 173196	WormBaseID:	WBGene00010808	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	425	Identity:	84/425 - (19%)
Similarity:	161/425 - (37%)	Gaps:	122/425 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 LVVDGKQGQQVAPGGGQNTAIVLPQQQGAGG----APGAPKTPADMVQQLTQQQQQQQQQVHQQQ 723
            :::.|:.|:            :..:..|:||    .|.|.||  ..||.:..:.:.::::...::
Worm   333 MIMRGRDGR------------LQKETSGSGGFEKMQPVAVKT--FQVQWVEMKTEFEKKKASTER 383

  Fly   724 VQQQELRRFDG--MSQQVVAG------------GMQQQQQQGLP-PVIRIQGAQPAVRVLGPGGP 773
            |:.|...:.:|  :.:.|:|.            |:.|.|:  :| ...|::.|:
Worm   384 VEPQHPVQTEGEDIMETVLAMVESFNCDLRKELGLTQDQE--IPRKAPRVESAE----------- 435

  Fly   774 GGPSGPNVLPNDVNSLHQQQQQMLQQQQQQGQNRRRGGLA--------TMVE-----QQQQHQQQ 825
               :..|::.|      .::.|:.:..::.......||..        ||.|     :.:...|.
Worm   436 ---TEENIVKN------LEKLQIAKDPEEPTTAASEGGNTYGYQELDDTMSEGLLEKEAESKHQD 491

  Fly   826 QQQPNPAQLGGNIPAPLSVNVGGFGNTNFGGAAAGGAVGANDK----QQLKV------AQVHP-Q 879
            ..:|.|.:                 |..:     ...|.|.||    ::||.      ||:.. :
Worm   492 ANEPEPVK-----------------NVTY-----EPDVAAMDKKKKRRELKSRLNKINAQIDELE 534

  Fly   880 SHGVGAGG-----ASAGAGASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGG--NGG 937
            ...:...|     :|:.......||.|.:|..:..:|....|...|..:   :..|..|.  .|.
Worm   535 KRRMERAGKKQVVSSSVPSEEAAQVEAPASPALAENTNQISNEETPKID---IFEGYNGSFLFGT 596

  Fly   938 NTGPPGDNEKDWRESVTADLRNHLVHKLVQAIFP-TSDPTTMQDKRMHNLVSYAEKVEKDMYEMA 1001
            ||      .|:|   :..|:|||:|.||::|.:| ..:...|..:....|::.|.|.|.::.|.:
Worm   597 NT------SKEW---IVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEAS 652

  Fly  1002 KSRSEYYHLLAEKIYKI-QKELEEKRLKRKEQHQQ 1035
            ..|.|||.|:...:.:| :|.|::.:...:..|||
Worm   653 NDRDEYYRLMQLTVDQILKKTLKKDQRATEHNHQQ 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354	25/79 (32%)
		Bromo_cbp_like	1705..1812	CDD:99927
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
sepa-1	NP_493339.1	KIX	600..676	CDD:280354	25/78 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900