Protein Alignment nej and Kat2a

DIOPT Version :9

• Sequence 1: NP_001188575.1
• Gene: nej / 43856
• FlyBaseID: FBgn0261617
• Length: 3282
• Species: Drosophila melanogaster
• Sequence 2: XP_017169759.2
• Gene: Kat2a / 14534
• MGIID: 1343101
• Length: 907
• Species: Mus musculus
• Alignment Length: 1153
• Identity: 194/1153 - (16%)
• Similarity: 318/1153 - (27%)
• Gaps: 453/1153 - (39%)

  Fly   831 PAQLGGNIP---APLSVNVGGFGNTNFGGAAAGGAVGANDKQQLKVAQVHP-QSHGVGAGGASAG 891
            |:..|...|   ||::....|.|......|....|..:.....:..||..| .|.........|.
Mouse    16 PSCAGAVTPAHCAPVAHAALGLGARRRSAAGEAMAEPSQAPNPVPAAQPRPLHSPAPAPTSTPAP 80

  Fly   892 AGASGGQVA-----AGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRE 951
            :.||....|     |.:....||.:|||              ||||.|:||:...||.:::....
Mouse    81 SPASASTPAPTPAPAPAPAAAPAGSTGS--------------GGAGVGSGGDPARPGLSQQQRAS 131

  Fly   952 SVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEK-DMYEMAKSRSEYYHLLAEKI 1015
            ...|.:|.                           :..|:|:|| .::...|:..
Mouse   132 QRKAQVRG---------------------------LPRAKKLEKLGVFSACKANE---------- 159

  Fly  1016 YKIQKELEEKRLKRKEQHQQMLMQQQGVANPVAGGAAGGAGSAAGVAGGVVLPQQQQQQQQQQQQ 1080
                                 ..:..|..||..                   |...:...||...
Mouse   160 ---------------------TCKCNGWKNPKP-------------------PTAPRMDLQQPAA 184

  Fly  1081 QGQQPLQSCIHP---SISPMGGVMPPQQLRPQGPPGILGQQTAAGLGVGVGVTNNMVTMRSHSPG 1142
            ...:..:||.||   .:|.:..|...:..|.              ||:.|.|.|..:::......
Mouse   185 NLSELCRSCEHPLADHVSHLENVSEDEINRL--------------LGMVVDVENLFMSVHKEEDT 235

  Fly  1143 GN------MLALQQQQRMQFPQQQQQQPPGSGAGKMLVGPPGPSPGGMVVNPALSPYQTTNVLTS 1201
            ..      :..|.::..:     |..:|...|:    :|.|              |::..|:
Mouse   236 DTKQVYFYLFKLLRKCIL-----QMTRPVVEGS----LGSP--------------PFEKPNI--- 274

  Fly  1202 PVPGQQQQQQFINANGGTGANPQLSEIMKQRHIHQQQQQQQQQQQQGMLLPQSPFSNSTPLQQQQ 1266
                :|....|:.              .|..|:..:::|...:..:..||..:.:...||.|.:|
Mouse   275 ----EQGVLNFVQ--------------YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQ 321

  Fly  1267 QQQQQ----------------------QQQQQQATSNSFSSPMQQQQQGQQQQQ----------- 1298
            :.|.:                      ....:..|::.|...:.:......::|
Mouse   322 RSQSEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDK 386

  Fly  1299 ---QKPGSVLNNMPPTPTSLEALNAGAGAPGTGGSASNVTVSAPSPSPGFLSNGPSIGTPSNNNN 1360
               :|...:|.:.|...:.||....||              ::|....||
Mouse   387 LVPEKRTLILTHFPKFLSMLEEEIYGA--------------NSPIWESGF--------------- 422

  Fly  1361 NSSANNNPPSVSSLMQQPLSNRPGTPPYIPASPVPATSASGLAASSTPASAAATCASSGSGSNSS 1425
                 ..|||..:.:                .|.|||.::.:..|.:|        |.|.|||||
Mouse   423 -----TMPPSEGTQL----------------VPRPATVSATVVPSFSP--------SMGGGSNSS 458

  Fly  1426 SGATAAGA---------------------------------------SSTSSSSSAGSGTPLSSV 1451
            ....:||.                                       :.|..::..|..|.|.|.
Mouse   459 LSLDSAGTEPMPAGEKRKLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSA 523

  Fly  1452 STPTSATMATSSGGGGGGGGNAGG-------GSSTTPASN------------------------- 1484
            :.....|....         ...|       |:|.||.:|
Mouse   524 NAARDETARLE---------ERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEY 579

  Fly  1485 -----------PLLLMSGGTAGGGTGATTTTSTSSSSRMMSSSSSLSSQMAALEAAARDNDDETP 1538
                       .|.|:..|...||.          ..||..:.........|:
Mouse   580 IARLVFDPKHKTLALIKDGRVIGGI----------CFRMFPTQGFTEIVFCAV------------ 622

  Fly  1539 SPSGENTNGSG-----------------------GSGNAGGMASKGKLDSIKQDDDIKKEFMDDS 1580
             .|.|...|.|                       .....|....:|....||........::.|.
Mouse   623 -TSNEQVKGYGTHLMNHLKEYHIKHSILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDY 686

  Fly  1581 CGGNNDSSQMDCSTGG-----------GKGKNVNNDGTSMIKMEI-KTEDGL----DGEVKIKTE 1629
            .|    ::.|:|....           .|.|.:........:.:| |...||    :|..:|..|
Mouse   687 EG----ATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVE 747

  Fly  1630 AM-DVDEAGGSTAGEHHGEGGGG---SGVGGGKDNINGAHDGGATGGAVDIKPKTETKPLVPEPL 1690
            :: .:.|.|....|:      ||   :.||..:|..:.:  .|.||          .|||
Mouse   748 SVPGIREQGPWLRGQ------GGILRAWVGILRDAFSPS--AGETG----------WKPL----- 789

  Fly  1691 APNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGT 1755
                |.:|.|...:|::|.|.|...|.:: :..|.:.||..||....  .|||:|:::.|:||.|
Mouse   790 ----GKEKGKELKDPDQLYTTLKNLLAQI-KSHPSAWPFMEPVKKSE--APDYYEVIRFPIDLKT 847

  Fly  1756 IRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVF 1803
            :...:::..|.....:|.|:..:..|...||...|...|..:.|.:.|
Mouse   848 MTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFF 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354	7/78 (9%)
		Bromo_cbp_like	1705..1812	CDD:99927	28/99 (28%)
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
Kat2a	XP_017169759.2	PCAF_N	129..378	CDD:399460	48/383 (13%)
		COG5076	533..902	CDD:227408	80/429 (19%)
		Bromo_gcn5_like	802..901	CDD:99941	27/97 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900