DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nej and ZK1010.10

DIOPT Version :9

Sequence 1:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster
Sequence 2:	NP_001255185.1	Gene:	ZK1010.10 / 13191684	WormBaseID:	WBGene00164985	Length:	194	Species:	Caenorhabditis elegans

Alignment Length:	130	Identity:	36/130 - (27%)
Similarity:	64/130 - (49%)	Gaps:	11/130 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  2402 KQSIQRCIQSLAHACQCRDAN---CRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHA 2463
            ::.|:...:.|.||..|..|:   |.|  |.:||.|:.||:.|.|:....|.:|..::::..:||
Worm    43 REKIEIVERGLLHALYCPRAHHSCCLL--CTRMKFVISHTRKCVRRRREVCEVCSTVVSITVFHA 105

  Fly  2464 KNCEEQKCPVPFCPNIKHKLKQQQ--SQQKFQQQQLLRRRVALMSRTAAPAAL----QGPAAVSG 2522
            :.|:|::|.:|||..|:..::...  |...:....|:.|.|..:...:....|    .|.|.|:|
Worm   106 RVCDEEECQIPFCHEIRDAMETYSAGSYHLYDLDHLVHRVVRRLQDLSPDQQLSDEEDGEAEVAG 170

Fly 2523 2522
Worm 171 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927
		RING_CBP-p300	1824..1906	CDD:276805
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717	24/74 (32%)
ZK1010.10	NP_001255185.1	zf-TAZ	55..115	CDD:366931	21/61 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900