Protein Alignment a and Pard3b

DIOPT Version :9

• Sequence 1: NP_001014543.1
• Gene: a / 43852
• FlyBaseID: FBgn0000008
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: XP_006496361.1
• Gene: Pard3b / 72823
• MGIID: 1919301
• Length: 1238
• Species: Mus musculus
• Alignment Length: 481
• Identity: 103/481 - (21%)
• Similarity: 152/481 - (31%)
• Gaps: 180/481 - (37%)

  Fly   923 QEQEAQGEDQCDARSMASVST----------------MPTPMPLMQHRRSSTP---RHSLDVGAP 968
            |:.|:.|.:..|.:|..:..|                :.||..|    :..||   |.|.|....
Mouse   121 QKTESPGGNPADRQSPDAFETEVAAQLAAFKPVGGEIVVTPSAL----KLGTPLLVRRSSDPAPG 181

  Fly   969 EHELLRRRARSSSGQRSLALTPTPLFASGSSSCSSSPNHRLLDNE-------NDPANDTDSYTPV 1026
            .|...:....|.|||   :|.|..|     .|..:..|...::.|       :.|.::....|
Mouse   182 PHADAQPSTASLSGQ---SLKPVVL-----DSTQNVENKEAMNGEQAGLLSLHRPKDELSDMT-- 236

  Fly  1027 YANRAASVCVASSLADDEKWQLLARKRCSEGSALSATPNPQQFGQRTHYARNSINLANSHYRSLR 1091
               ||..:                   ..||..|.....|
Mouse   237 ---RAVEI-------------------SGEGDPLGIHVVP------------------------- 254

  Fly  1092 FAHSRLSSSRLSLFMQA-PPNSLTVGEGV------------ANTPSSTATTTTDLTNQQQQQ--- 1140
             ..|.||...|.||::. ..||....||:            ......|.....|:..|..:.
Mouse   255 -FFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSV 318

  Fly  1141 -------QNQQQTHQSLYIKHSPKSVSLFSPNPYVNASSSPASASTSAGAGSSLAPPAAALMHHR 1198
                   ||::|..:|:.   .|  :::|..|.  .||.:.|            ||||..    :
Mouse   319 ILHVLLPQNREQYEKSVI---GP--LNIFGNND--GASRTKA------------APPARG----K 360

  Fly  1199 PSLPVAKLTIRDEEMAEVIRASMSEGSGRCTPK-------------------------------- 1231
            |.|....||          |||..||....:|:
Mouse   361 PGLKAVHLT----------RASSPEGEEPASPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAK 415

  Fly  1232 --TITFFKGPGLKSLGFSIVGGRDSPKGNMGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQG 1294
              .|...|||  :.|||::|....|..|...||||.:.|.|.|..||.||:||.|:|:||..|.|
Mouse   416 KIKIDLKKGP--EGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTG 478

  Fly  1295 MSHAETIGLFKNVREGTIVLKILRRK 1320
            .:..|.:.:.::.::|..|..::.|:
Mouse   479 RTQEELVAMLRSTKQGETVSLVIARQ 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
		PDZ_signaling	1230..1317	CDD:238492	33/120 (28%)
Pard3b	XP_006496361.1	DUF3534	2..74	CDD:338230
		PDZ_signaling	236..323	CDD:238492	20/136 (15%)
		PDZ	415..504	CDD:214570	32/90 (36%)
		PDZ_signaling	536..624	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900