DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a and Pdzk1

DIOPT Version :9

Sequence 1:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster
Sequence 2:	NP_113900.1	Gene:	Pdzk1 / 65144	RGDID:	70924	Length:	523	Species:	Rattus norvegicus

Alignment Length:	130	Identity:	33/130 - (25%)
Similarity:	55/130 - (42%)	Gaps:	26/130 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1188 APPAAALMHHRPSLPVAKLTIRDEEMAEVIRASMSEGSGRCTPKTITFFKGPGLKSLGFSIVGGR 1252
            :|...||...:|.|                  .|:.|...|....:.:....| .|.|||:
  Rat   108 SPREPALNEKKPDL------------------GMNGGVETCAQPRLCYLVKEG-NSFGFSL---- 149

  Fly  1253 DSPKGNMGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQGMSHAETIGLFKNVREGTIVLKIL 1317
            .:.:|..|:|:..:.|.|.|...|.| |.|.::|:||.:|:..||.|.:.  |..:.|:.::.:|
  Rat   150 KTIQGKKGVFLTDITPQGVAMKAGVL-ADDHLIEVNGENVENASHEEVVE--KVTKSGSRIMFLL 211

Fly 1318 1317
Rat 212 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492	24/86 (28%)
Pdzk1	NP_113900.1	PDZ_signaling	7..87	CDD:238492
		PDZ	132..212	CDD:214570	25/88 (28%)
		PDZ_signaling	242..320	CDD:238492
		PDZ	375..455	CDD:214570
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	479..523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900