DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster
Sequence 2:	NP_067605.1	Gene:	Slc9a3r1 / 59114	RGDID:	708538	Length:	356	Species:	Rattus norvegicus

Alignment Length:	109	Identity:	30/109 - (27%)
Similarity:	50/109 - (45%)	Gaps:	7/109 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1220 SMSEGSGRCTPKTITFFKGPGLKSLGFSIVGGRDSPKGNMGIFVKTVFPSGQAADDGTLQAGDEI 1284
            |....:|...|:.....|||  ...||.:.|    .||.:|.|::.|.| |..|:...|.|||.:
  Rat     2 SADAAAGEPLPRLCCLEKGP--NGYGFHLHG----EKGKVGQFIRLVEP-GSPAEKSGLLAGDRL 59

  Fly  1285 VEINGNSVQGMSHAETIGLFKNVREGTIVLKILRRKLQKAKSMG 1328
            ||:||.:|:..:|.:.:...:.......:|.:.....::.|.:|
  Rat    60 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLKKLG 103

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492	26/86 (30%)
Slc9a3r1	NP_067605.1	PDZ_signaling	12..91	CDD:238492	26/85 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..142
		PDZ_signaling	149..228	CDD:238492
		EBP50_C	232..356	CDD:286142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..356
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900