DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a and Pdzk1

DIOPT Version :9

Sequence 1:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster
Sequence 2:	NP_001139473.1	Gene:	Pdzk1 / 59020	MGIID:	1928901	Length:	519	Species:	Mus musculus

Alignment Length:	114	Identity:	29/114 - (25%)
Similarity:	50/114 - (43%)	Gaps:	14/114 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1210 DEEMAEVIRASMSEGSGR------CTPKTITFFKGPGLKSLGFSIVGGRDSPKGNMGIFVKTVFP 1268
            |:...|........|.|.      |....:.:....| .|.|||:    .:.:|..|:::..:.|
Mouse   106 DQSQREAALNDKKPGPGMNGAVEPCAQPRLCYLVKEG-NSFGFSL----KTIQGKKGVYLTNIMP 165

  Fly  1269 SGQAADDGTLQAGDEIVEINGNSVQGMSHAETIGLFKNVREGTIVLKIL 1317
            .|.|...|.| |.|.::|:||.:|:..||.|.:.  |..:.|:.::.:|
Mouse   166 QGVAMKAGVL-ADDHLIEVNGENVENASHEEVVE--KVTKSGSRIMFLL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492	23/86 (27%)
Pdzk1	NP_001139473.1	PDZ_signaling	7..87	CDD:238492
		PDZ	132..212	CDD:214570	24/88 (27%)
		PDZ_signaling	242..320	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..374
		PDZ_signaling	376..455	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	479..519
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900