Protein Alignment a and Tamalin

DIOPT Version :9

• Sequence 1: NP_001014543.1
• Gene: a / 43852
• FlyBaseID: FBgn0000008
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_062391.3
• Gene: Tamalin / 56149
• MGIID: 1860303
• Length: 392
• Species: Mus musculus
• Alignment Length: 206
• Identity: 60/206 - (29%)
• Similarity: 85/206 - (41%)
• Gaps: 42/206 - (20%)

  Fly  1153 KHSPKSVSLFSPNPYVNASSSPASASTSAGAGSSLAPPAAALMHHRPSLPVAKL--TIRDEEMAE 1215
            |...|..:..:|:|...|..|.|:.:....:|    |||||.   .|..|..:|  .:.|...||
Mouse     8 KLQQKEEATAAPDPAGRAPDSEAARAAPLPSG----PPAAAA---PPGAPGEELYAALEDYHPAE 65

  Fly  1216 VIRA--------SMSEGSG------RCTP----KTITFFKGPGLKSLGFSI----VGGRDSPKGN 1258
            :.||        ...:|||      ..:|    |.:|..||.. ::.||.|    :..|:..:..
Mouse    66 LYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKGDN-QTFGFEIQTYGLHHREEQRVE 129

  Fly  1259 MGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQGMSHAETIGLFK---NVRE-----GTIVLK 1315
            |..||..|..|..|...| |..||.|..:||.:|:|:.|.|.:.:.|   ||..     ||.:.|
Mouse   130 MVTFVCRVHESSPAQLAG-LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRK 193

  Fly  1316 I-LRRKLQKAK 1325
            . |..:||..|
Mouse   194 AELEARLQYLK 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
		PDZ_signaling	1230..1317	CDD:238492	32/103 (31%)
Tamalin	NP_062391.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		14/48 (29%)
		PDZ_signaling	99..184	CDD:238492	28/86 (33%)
		Interaction with PSCD3. /evidence=ECO:0000269|PubMed:10828067	180..257		8/25 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..315

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900