Protein Alignment a and lnx2a

DIOPT Version :9

• Sequence 1: NP_001014543.1
• Gene: a / 43852
• FlyBaseID: FBgn0000008
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_001106696.2
• Gene: lnx2a / 553331
• ZFINID: ZDB-GENE-060228-2
• Length: 737
• Species: Danio rerio
• Alignment Length: 576
• Identity: 127/576 - (22%)
• Similarity: 190/576 - (32%)
• Gaps: 192/576 - (33%)

  Fly   788 IGIVLSPKTVMTNSNEQQYRYLIVELEPYGMAQKDGRLRLGDEIVNVNGKHLRGI-QSFAEVQRL 851
            |.||...:|.:.|       .:|.|:...|:..:||||..||:|:.||...:..: .:||.
Zfish   284 ISIVGGNETPLIN-------VVIQEVYRDGVIARDGRLLAGDQILQVNNVDISNVPHNFAR---- 337

  Fly   852 LSSFVDNCIDLVIAHDEVTTVTDFYTKIRIDGMSTQRHRLSYVQRTQSTDSLSSMQSLQLQQERI 916
             |:....|                                               .:|||...|
Zfish   338 -STLARPC-----------------------------------------------ATLQLTVLR- 353

  Fly   917 QGHNTEQEQEAQGEDQCDAR---SMASVSTMPTPMPLMQHRRSSTPRHSLDVGAPEHELLRRRAR 978
                         |.:|.||   :.||....|..:.:..|:|.|:.:..:       :|:||  .
Zfish   354 -------------ERRCSARPPAATASPKGSPASIRITLHKRESSEQLGI-------KLVRR--T 396

  Fly   979 SSSGQRSLALTPTPLFASGSSSCSSSPNHRLLD-NENDPANDTDSYTPVYANRAASVCVASSLAD 1042
            ..:|...|.|....|.|.....||   |.|:|. ||:|..:.|...       ||.:..||.
Zfish   397 DEAGVFILDLLEGGLAAKDGRLCS---NDRVLAVNEHDLRHGTPEL-------AAQIIQASG--- 448

  Fly  1043 DEKWQLLARKRCSE------GSAL---------------SATPNPQQFGQRTHYARNS------- 1079
             |:..||..:...:      ||.|               :|||:|.   ...|.||:|
Zfish   449 -ERVNLLISRSSKQTMAVHTGSTLTRDIWSHDHIPPLPSTATPSPV---PSLHLARSSTQRDLSQ 509

  Fly  1080 -INLANSHYRSLRFAHSRLSSSRLSLFMQAPPNSLTVGEGVANTPSSTATTTTDLTNQQQQQQNQ 1143
             :|....|....:..|..|              .:||..|..:.........|.:
Zfish   510 CVNCKEKHITVKKEPHESL--------------GMTVAGGRGSKSGELPIFVTSV---------- 550

  Fly  1144 QQTHQSL----YIKHSPKSVSLFSPN-PYVNASSSPASASTSAGAGSSLAPPAAALMHHRPSLPV 1203
             |.|..|    .||.....:|:...: .|::.|.:..:..:||.:.|.........|...|.|
Zfish   551 -QPHGCLSRDGRIKRGDVLLSINGQDLTYLSHSEAVGTLKSSATSCSVQLKALEVTMVEEPGL-- 612

  Fly  1204 AKLTIRDEEMAEVIRASMSEGSGRCTPKTITFF----------------KGPGLKSLGFSIVGGR 1252
                  |||:   :....::.....:|..:.:.                ..||  |.|||||||.
Zfish   613 ------DEEL---LPPHENDYDASWSPSWVLWLGLPSYLHSSHEIVLRRSHPG--SWGFSIVGGY 666

  Fly  1253 DSPKGNMGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQGMSHAETIGLFKNVR 1308
            :....|...|:||:.....|..||.|:.||.||.:||.|..||||:..:.:.|..|
Zfish   667 EENHSNQAFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTAGMSHSALVPMLKEQR 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492	21/77 (27%)
		PDZ_signaling	1230..1317	CDD:238492	32/95 (34%)
lnx2a	NP_001106696.2	zf-RING_2	49..87	CDD:290367
		PDZ	267..353	CDD:214570	24/127 (19%)
		PDZ_signaling	375..455	CDD:238492	26/102 (25%)
		PDZ_signaling	515..600	CDD:238492	18/109 (17%)
		PDZ_signaling	646..730	CDD:238492	31/79 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19964
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000