Protein Alignment a and dysc

DIOPT Version :9

• Sequence 1: NP_001014543.1
• Gene: a / 43852
• FlyBaseID: FBgn0000008
• Length: 1329
• Species: Drosophila melanogaster
• Sequence 2: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Alignment Length: 1199
• Identity: 239/1199 - (19%)
• Similarity: 367/1199 - (30%)
• Gaps: 427/1199 - (35%)

  Fly   282 NSLPATEASRNSNSSSNMNGSSNSNSLDVSNSNSHSGSSTSLASTTRNVFTWGKRMSRKLDLLKR 346
            |:..|..||.....|  |.|:.:|:|:....|...||..                       |:.
  Fly    43 NATAAAAASFGLGPS--MGGTQSSSSVPTGGSAGLSGHH-----------------------LRS 82

  Fly   347 SDSPAAAHKSHSDLRSLFH--SPTHHKSGSGGSSGPSSAKASASPTGGHQNSSGST-----TSTL 404
            |.:|..:.....|:...|.  ||   ..|||...| |||.|..|..|   ||:.|.     .|.|
  Fly    83 SGAPGPSSFEAEDIGMAFGMISP---PPGSGPYVG-SSAAAGGSRVG---NSTSSLRGAGGRSGL 140

  Fly   405 KKCKSGPIETIKQRHQQQQQQQQSVQDVGTGQSQSAQSTPTHQFQAAARPQKALKNFFHRIGSTG 469
            .....|...||.:|                      ..:|.:.|.:|..|.|.           |
  Fly   141 YYSPPGTSYTIVER----------------------PHSPHYYFNSAGVPTKG-----------G 172

  Fly   470 MLNHRSHNLLKASEAAQQATPAATTLYRSSSTSQLSSSSYVKCDDPTEGLNLQREQREQRLPRIA 534
            .|..|....|.:|.|:..|...|.||..|::.|..|...:..    :.|...:....||.|....
  Fly   173 SLPGRGSAYLSSSPASHMAAGTAGTLPTSTAASGRSMGQHAS----SNGNKKRPISPEQVLRMFG 233

  Fly   535 SLKSSSCDDIAKVSSCLTASTSSGSAAGSLGSPPSSAAAGGGGTANSGQHDPSRRGAFPYAFLRS 599
            :.:|||.                         |.||.....|||     .|..|.|.      ||
  Fly   234 ATQSSSV-------------------------PTSSYHYSNGGT-----RDRDRTGR------RS 262

  Fly   600 RLSVLPEENHGNVPGHLKQQIQRQREQHQQHQRDLLQQEQTSSPLPQRRSPEQAMLNNVSRNDSI 664
            ..|..|...|         ||.|.||:    :||             |..|.   ::.::.....
  Fly   263 PASSPPSTTH---------QIYRDRER----ERD-------------RSVPN---IHELTTRTVS 298

  Fly   665 TSKDWEPLYQRLSSCLSSNESGYDSDGGATGARLGNN-----LSISGGDTESIASGT-------- 716
            .|:| :.:......|:   :.|.||..|...:|:..|     ..:..|||....:||
  Fly   299 MSRD-QQIDHGFGICV---KGGKDSGLGVYISRIEENSVAERAGLRPGDTILEVNGTPFTSINHE 359

  Fly   717 --LKRNSLISLSSSEGVGM---------------GMG---------------------------- 736
              |||...| |.||..:.|               |.|
  Fly   360 EALKRCVQI-LKSSRQISMTVRAPPTLNSTAPLHGFGPPSRDPMYASMAPPLHPQNQAAAAAAAA 423

  Fly   737 MSLGLGAP-------STRNSSICSAPVSLGGYNYDYETETIRRRFRQVKLERKCQEDYIGIVLSP 794
            .:.|.|.|       ..|:....|.|:..||          ||..|:.::.|      :.:::.|
  Fly   424 AASGAGLPFRQTCSWMDRHGRPASPPMEYGG----------RRSERRDRIRR------VELLIEP 472

  Fly   795 ----KTVMTNSNEQQYRYLIVELEPYGMAQKDGRLRLGDEIVNVNGKHLRGIQSFAEVQRLLSSF 855
                ..::....|......:..::...:|.:.| |.:||||:.|||      |||.:|..
  Fly   473 GQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSG-LMIGDEILEVNG------QSFLDVTH----- 525

  Fly   856 VDNCIDLVIAHDEVTTVT------------------DFY----TKIRIDG-MSTQ---------- 887
             |..:..:..|..::.|.                  |.|    |:.|..| ::|.
  Fly   526 -DEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLP 589

  Fly   888 RHR---LSYVQRTQSTDSLSSMQSLQLQQERIQGHN-----TEQEQEAQGEDQCDARSMASVSTM 944
            ||.   |||.....|..:::....:.:..|.:..:.     ||..:....||:.....:. ....
  Fly   590 RHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEKHTLVTEIRELVFPEDRTRYDELV-YRRE 653

  Fly   945 PTPMPLMQHRRSSTPRHSLDVGAPEHELLRRRARSSSGQRSLALTPTPLFASGSSSCSSSPN--- 1006
            ..|..:.:|||...|...|.|.|.:.|::....||.|....|.:|.|.::...:......|.
  Fly   654 RDPYSVDRHRRKGDPARDLPVTADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPHRPMSAG 718

  Fly  1007 ---HRLLDNENDPANDTDSYTPVYANRAASVCVASSLADDEKWQLLARKRCSEGSALSATPNPQQ 1068
               ||     :.||    |:....:|:::|                           |.:|..||
  Fly   719 PILHR-----SQPA----SHYQTGSNQSSS---------------------------SLSPPQQQ 747

  Fly  1069 FGQRTHYARNSINLANSHYRSLRFA-------------HSRLSSSRLSLFMQAPPNSLTVGEGVA 1120
            ..|:.||        ..|:.|||..             |..|..|:|. |.|
  Fly   748 QQQQQHY--------QPHHASLRHLGGIGGNVGSGRHHHHPLGPSQLK-FRQ------------- 790

  Fly  1121 NTPSSTATTTTDLTNQQQQQQNQQQTHQSLYIKHSPKSVSLFSPNPYVNASSSPASASTSAGAGS 1185
                         |...|||:.....|::.  :.|...:..:.|:.....::..:.:......|.
  Fly   791 -------------TKDNQQQEYGCDEHRTR--RGSETLLPEYEPDAEQELATKLSRSFDMKEEGG 840

  Fly  1186 SLAPPAAALMHHRPSLPVAKLTIRDEEMAEVIRASMSEGSGRCTPKT----------------IT 1234
            :|........|.                 .:.|.|..:..|..|.:|                ||
  Fly   841 TLLGDKGVRRHQ-----------------SMQRLSAEQNGGSTTEQTHEHNPNVVPDHRGNLHIT 888

  Fly  1235 FFKGPGLKSLGFSIVGGRDS----PKGNMGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQGM 1295
            ..|...:  ||.:|.||.::    |:      :..:..:|.|.:.|.|:.|..|:|::|..|:|:
  Fly   889 VKKTKPI--LGIAIEGGANTKHPLPR------IINIHENGAAFEAGGLEVGQLILEVDGTKVEGL 945

  Fly  1296 SHAETIGL----FKNVREGTIVLKILRRK 1320
            .|.|...|    |.|..:..|...::..|
  Fly   946 HHQEVARLIAECFANREKAEITFLVVEAK 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492	19/93 (20%)
		PDZ_signaling	1230..1317	CDD:238492	26/110 (24%)
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	22/90 (24%)
		PDZ_signaling	466..543	CDD:238492	19/89 (21%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	13/80 (16%)
		PDZ_signaling	886..971	CDD:238492	25/92 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900