DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster
Sequence 2:	NP_036160.1	Gene:	Slc9a3r1 / 26941	MGIID:	1349482	Length:	355	Species:	Mus musculus

Alignment Length:	201	Identity:	51/201 - (25%)
Similarity:	78/201 - (38%)	Gaps:	47/201 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1123 PSSTATTTTDLTNQQQQQQN----QQQTHQSLY--IKHSPKSVSLFSPNPYVNASSS-------- 1173
            |.|.|..:..|...:..:.|    :::|||.:.  |:.:..:|.|...:|..:....
Mouse    44 PGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIRE 108

  Fly  1174 ----PASASTSAGAGSSLAPPAAALMHHRPSLPVAKLTIRDEEMAEVIRASMSEGSGRCTPKTIT 1234
                |...|..|      .|||||..|.          ..|:..||  ::.:.|    ..|:..|
Mouse   109 ELLRPQEKSEQA------EPPAAADTHE----------AGDQNEAE--KSHLRE----LRPRLCT 151

  Fly  1235 FFKGPGLKSLGFSIVGGRDSPKGNMGIFVKTVFPSGQAADDGTLQAGDEIVEINGNSVQGMSHAE 1299
            ..|||  ...||::    .|.|...|.|::.|.|...|...| |:|.|.|||:||..::|..|.:
Mouse   152 MKKGP--NGYGFNL----HSDKSKPGQFIRAVDPDSPAEASG-LRAQDRIVEVNGVCMEGKQHGD 209

  Fly  1300 TIGLFK 1305
            .:...|
Mouse   210 VVSAIK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492	26/76 (34%)
Slc9a3r1	NP_036160.1	PDZ_signaling	12..91	CDD:238492	11/46 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..146		13/57 (23%)
		PDZ_signaling	147..226	CDD:238492	26/76 (34%)
		EBP50_C	230..355	CDD:286142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	244..355
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900