DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment a and C46H11.6

DIOPT Version :9

Sequence 1:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster
Sequence 2:	NP_491502.1	Gene:	C46H11.6 / 183523	WormBaseID:	WBGene00016730	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	56/334 - (16%)
Similarity:	115/334 - (34%)	Gaps:	99/334 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   697 RLGNNLSISGGDTESIASGTLKRNSLISLSSSEGVGMGMGMSLGLGAPSTRNSSICSAPVSLGGY 761
            |:..|..:|...|.|..:|.:..:.::.::.:.|                 |.|
Worm    50 RINENSMVSFLSTNSFYNGLILSDKIVKVNGASG-----------------NIS----------- 86

  Fly   762 NYDYETETIRRRFRQVKLERK---------------C--QEDYIGIVLSPK--------TVMTNS 801
              .|:||.::.....|::.|:               |  :.|....|:..:        ||....
Worm    87 --KYQTELMKGETCSVEVTRRKNIIPATRERLKKSGCVLRRDNTCFVIEVEKTSAMKSATVGVTV 149

  Fly   802 NEQQYRYLIVELEPYGMAQ-KDGRLRLGDEIVNVNGKHLRGIQSFAEVQRLLSSFVDNCIDLVIA 865
            ...|.|.::..:||..:|. ..||   ||.|:::|.:.:...:.       ...|:...:..::.
Worm   150 TYIQKRGIVTRIEPSSLASIFFGR---GDLIMDINEESILNAEK-------NDDFIREKLSGILK 204

  Fly   866 HDEVTTVTDFYTKIRIDGMSTQRHRLSYVQ---------------RTQSTDSLSSMQSLQ----L 911
            .::||.:.:  ..:.::..:|.||.:..|.               |..|....:.::.||    |
Worm   205 GEKVTFLVE--RPVSVESANTLRHLIESVAPDPDVKMANDAICIGRNASNMHYNVLKKLQPKSIL 267

  Fly   912 QQERIQGHNTEQEQEAQGEDQCDARSMASVSTMPTPMPLMQHRRSSTPRHSLDVGAPEHELLRRR 976
            .::..:|.|..:::..:...: :..:...:||           .:||...|.||...|.:.|:..
Worm   268 SRDVFKGKNPREKKPGKKLSK-EKDNTIKIST-----------ATSTANISTDVAEDEIDNLKNV 320

  Fly   977 ARSSSGQRS 985
            ...|...||
Worm   321 VTKSHAVRS 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492	19/115 (17%)
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492
C46H11.6	NP_491502.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900