Protein Alignment Sox102F and sox6

DIOPT Version :10

• Sequence 1: NP_001014695.1
• Gene: Sox102F / 43844
• FlyBaseID: FBgn0039938
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: XP_068078453.1
• Gene: sox6 / 567154
• ZFINID: ZDB-GENE-081120-6
• Length: 806
• Species: Danio rerio
• Alignment Length: 701
• Identity: 203/701 - (28%)
• Similarity: 283/701 - (40%)
• Gaps: 211/701 - (30%)

  Fly    11 EKEHSDLGMIKQLQLIRNRILSQAHYDSMTDIDAS-AQQQQQLQNVQRLQHESCLQELHNHLSSQ 74
            |||.....||.||..:|.::|  |.:|....:.|| .::|:|...:.|.|.|...::....|..|
Zfish   205 EKERQLSTMITQLISLREQLL--AAHDEQKKLAASQMEKQRQQMELARQQQEQIARQQQQLLQQQ 267

  Fly    75 YGAVRFTAANPQHQNQQAVSVSSGNLMPFLPAFLQPPMPNAQQLLQLIPGHENAQSVPTHHHSHP 139
            :..                     ||:              ||.:|.:.||.....:|...|..
Zfish   268 HKI---------------------NLL--------------QQQIQQVQGHMPPLMIPIFPHDQ- 296

  Fly   140 QSEAFSTHKMALAPMWSTAAVAAAHIQAALAAAAVAAANNNKNSSHFSNNTNIVGLATRGNEL-- 202
                            .|.|.|||..|..|....::....:.....|..:|.....|:..|.|
Zfish   297 ----------------RTLAAAAAAQQGFLFPPGMSYKPGDNYPVQFIPSTMAAAAASGLNPLQL 345

  Fly   203 --LNTDSDPQMEIGETRRGGNGGSCRSRPESPTYENPPYEILSYSHNTPPESPHGRTADCSKNFS 265
              |.......|::                 ||..:.||.          |:.|:.     :...|
Zfish   346 QQLYAAQLASMQV-----------------SPGAKMPPL----------PQPPNS-----AGQIS 378

  Fly   266 PSPTDNLSIASVSEAQ-DSEMDAPLNLS-KPK-GSPSSSPNSSSQRDHCENLTPVVSSPPLSWHQ 327
            ||...|...:|...|| ..|...||||| :|| ..|..||.|.:|     :|.|...|.|.|..:
Zfish   379 PSGLKNEKRSSTPLAQVKEEGTQPLNLSARPKTAEPIKSPTSPTQ-----SLFPGSKSSPNSLSK 438

  Fly   328 GQPHYAEIELPLLKSHGRVWNSAVACSGGSRATRVSRDSV------------------------- 367
            .    .:|..| :...||..:..:..|..|.|....:|:|
Zfish   439 S----GDIPSP-IGGLGRGSSLDILSSLNSTALFGDQDAVMKAIQEARKMREQIQREQLQHHQQG 498

  Fly   368 -------------NSCGTNSERSAALDPESL--------NSGQLG----PVPASPSSQPLRQGNG 407
                         |:|.|..|||   ..::|        ..|::|    .:......:..|:.||
Zfish   499 MEVKLSALTSMGLNNCRTEKERS---HYDNLGHHLSKLGEDGKIGHRVIDLTRPEDFEGCRELNG 560

  Fly   408 -----HGH-----GG-----------NHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNS 451
                 |.:     ||           ..|...::||||||||||||||||||||||:|.||||||
Zfish   561 CADKPHQYYCWPTGGASTTEARVYREPRGRNSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNS 625

  Fly   452 NISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLM 516
            |||||||:|||:|:|.:||||||||:||||:|:|::|:|:|:||||||||:||||:||||||.:|
Zfish   626 NISKILGSRWKSMTNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIIDGKKLRISEYKQMM 690

  Fly   517 RNRRAEMRQLWCRTGGVSGGSGSLCADACPKGSGGSNSQVAVAAAAAVYH--LQDMASSAASTAH 579
            |:||.||||.:  |.|..                 ..:|:.:..:|.|.:  ...||::..|...
Zfish   691 RSRRQEMRQFF--TVGQQ-----------------PQTQIPITTSAGVVYPGAITMATTTPSPHM 736

  Fly   580 GHDCGH-------TPP--QQFF---YPPESLSPSGFSSDEVELASQRELDD 618
            ..||..       |.|  |..|   ..|.::.||...:.|.|:....:.:|
Zfish   737 TSDCSSASASPEPTIPVIQSTFNMKMEPGTMVPSDAVNGEDEMDMYEDFED 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	HMG-box_EGL13-like	421..498	CDD:438848	61/76 (80%)
sox6	XP_068078453.1	HMG-box_SoxD	596..672	CDD:438839	60/75 (80%)