DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox102F and sox21b

DIOPT Version :9

Sequence 1:	NP_001014695.1	Gene:	Sox102F / 43844	FlyBaseID:	FBgn0039938	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001009888.1	Gene:	sox21b / 406246	ZFINID:	ZDB-GENE-040429-1	Length:	245	Species:	Danio rerio

Alignment Length:	197	Identity:	69/197 - (35%)
Similarity:	100/197 - (50%)	Gaps:	36/197 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   419 SKP--HIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSK 481
            |||  |:||||||||||::.:|||:.:..|.||||.|||.|||.||.::.::|:|:.:|..||..
Zfish     2 SKPMDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66

  Fly   482 LHMEQHPDYRYRPRPKRTCIVDGKKM------RISEYKVLMRNRRAEMRQLWCRTGGVSGGSGSL 540
            :||::||||:||||.|...::...|.      .:.|::.|             :.||:..|
Zfish    67 MHMKEHPDYKYRPRRKPKTLMKKDKFAFPVAYNLGEHEAL-------------KVGGLPAG---- 114

  Fly   541 CADACPKGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCG----HTPPQQFFYPPESLSPS 601
               |..:....:..:.|.|||||...:....|.:|:.....|.|    ...|..|.|    .||.
Zfish   115 ---ALTESLMSNPDKAAAAAAAAAARVFFNPSMSANPYSFFDLGSKMTELSPPSFSY----ASPL 172

  Fly   602 GF 603
            |:
Zfish   173 GY 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	SOX-TCF_HMG-box	422..493	CDD:238684	38/70 (54%)
sox21b	NP_001009888.1	SOX-TCF_HMG-box	7..78	CDD:238684	38/70 (54%)
sox21b	NP_001009888.1	SOXp	77..>95	CDD:289133	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810