Protein Alignment Sox102F and sox17a

DIOPT Version :10

• Sequence 1: NP_001014695.1
• Gene: Sox102F / 43844
• FlyBaseID: FBgn0039938
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_989425.1
• Gene: sox17a / 395066
• XenbaseID: XB-GENE-484295
• Length: 383
• Species: Xenopus tropicalis
• Alignment Length: 229
• Identity: 69/229 - (30%)
• Similarity: 107/229 - (46%)
• Gaps: 60/229 - (26%)

  Fly   399 SQPLRQ-GNGH-----GHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKIL 457
            ::|:.. |.|.     |...:.|...::  |:||||||||||||||:::.:..||:||:.:||:|
 Frog    33 AEPMNSLGEGKLKSDAGSANSRGKAEAR--IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKML 95

  Fly   458 GARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAE 522
            |..|||::.|:|:|:.||..||...||:.||:|:||||.:               |.:.|.:||:
 Frog    96 GKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRR---------------KQVKRMKRAD 145

  Fly   523 ---MRQLWCRTGGVSGGSGSLCADACPKGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCG 584
               |.........|.|..|.:|.::...|                ||.|....|
 Frog   146 TGFMHMAEPPESAVLGTDGRMCLESFSLG----------------YHEQTYPHS----------- 183

  Fly   585 HTPPQQFFYPPESLSP--SGFS-----SDEVELA 611
            ..|....:..|::::|  .|:|     |..::||
 Frog   184 QLPQGSHYREPQAMAPHYDGYSLPTPESSPLDLA 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	HMG-box_EGL13-like	421..498	CDD:438848	42/76 (55%)
sox17a	NP_989425.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..58		4/20 (20%)
		HMG-box_SoxF_SOX17	55..135	CDD:438850	43/81 (53%)
		Sox17_18_mid	191..239	CDD:463454	7/27 (26%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:Q9H6I2	331..339
		Required for transcriptional activity and interaction with ctnnb1. /evidence=ECO:0000250|UniProtKB:Q3KQ35	332..337